Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis.

Borza DB, Bondar O, Colon S, Todd P, Sado Y, Neilson EG, Hudson BG. Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis. J Biol Chem. 2005 Jul 22; 280(29):27147-54.

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subject areas

Antigen-Antibody Reactions
Anti-Glomerular Basement Membrane Disease
Autoantibodies
Autoantigens
Autoimmune Diseases
Cell Line
Collagen Type IV
Dimerization
Epitopes
Humans
Immunoassay
Protein Denaturation
Protein Structure, Quaternary
Transfection

authors with profiles

Dorin-Bogdan Borza

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

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