"Protein Denaturation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.
| Descriptor ID |
D011489
|
| MeSH Number(s) |
E05.793.500 G01.154.651.750.500 G02.111.688.750.500
|
| Concept/Terms |
Protein Denaturation- Protein Denaturation
- Denaturation, Protein
- Denaturations, Protein
- Protein Denaturations
|
Below are MeSH descriptors whose meaning is more general than "Protein Denaturation".
Below are MeSH descriptors whose meaning is more specific than "Protein Denaturation".
This graph shows the total number of publications written about "Protein Denaturation" by people in this website by year, and whether "Protein Denaturation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 4 | 5 |
| 2004 | 1 | 4 | 5 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Denaturation" by people in Profiles.
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Stenzoski NE, Zou J, Piserchio A, Ghose R, Holehouse AS, Raleigh DP. The Cold-Unfolded State Is Expanded but Contains Long- and Medium-Range Contacts and Is Poorly Described by Homopolymer Models. Biochemistry. 2020 09 15; 59(36):3290-3299.
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Kumagai PS, Gutierrez RF, Lopes JLS, Martins JM, Jameson DM, Castro AM, Martins LF, DeMarco R, Bossolan NRS, Wallace BA, Araujo APU. Characterization of esterase activity from an Acetomicrobium hydrogeniformans enzyme with high structural stability in extreme conditions. Extremophiles. 2018 Sep; 22(5):781-793.
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Molugu SK, Li J, Bernal RA. Separation of E. coli chaperonin groEL from ?-galactosidase without denaturation. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Dec 15; 1007:93-9.
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McMicken B, Thomas RJ, Brancaleon L. Photoinduced partial unfolding of tubulin bound to meso-tetrakis(sulfonatophenyl) porphyrin leads to inhibition of microtubule formation in vitro. J Biophotonics. 2014 Nov; 7(11-12):874-88.
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Trujillo U, V?zquez-Rosa E, Oyola-Robles D, Stagg LJ, Vassallo DA, Vega IE, Arold ST, Baerga-Ortiz A. Solution structure of the tandem acyl carrier protein domains from a polyunsaturated fatty acid synthase reveals beads-on-a-string configuration. PLoS One. 2013; 8(2):e57859.
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Montecinos-Franjola F, Ross JA, S?nchez SA, Brunet JE, Lagos R, Jameson DM, Monasterio O. Studies on the dissociation and urea-induced unfolding of FtsZ support the dimer nucleus polymerization mechanism. Biophys J. 2012 May 02; 102(9):2176-85.
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Morleo A, Bonomi F, Iametti S, Huang VW, Kurtz DM. Iron-nucleated folding of a metalloprotein in high urea: resolution of metal binding and protein folding events. Biochemistry. 2010 Aug 10; 49(31):6627-34.
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Chaganty BK, Murthy AK, Evani SJ, Li W, Guentzel MN, Chambers JP, Zhong G, Arulanandam BP. Heat denatured enzymatically inactive recombinant chlamydial protease-like activity factor induces robust protective immunity against genital chlamydial challenge. Vaccine. 2010 Mar 08; 28(11):2323-9.
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Bonomi F, Iametti S, Ferranti P, Kurtz DM, Morleo A, Ragg EM. "Iron priming" guides folding of denatured aporubredoxins. J Biol Inorg Chem. 2008 Aug; 13(6):981-91.
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Gahl RF, Narayan M, Xu G, Scheraga HA. Dissimilarity in the oxidative folding of onconase and ribonuclease A, two structural homologues. Protein Eng Des Sel. 2008 Apr; 21(4):223-31.