| Item Type | Name |
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Academic Article
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HIV-1 infection induces a selective reduction in STAT5 protein expression.
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Academic Article
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Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation.
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Academic Article
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JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.
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Academic Article
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Targeted disruption of stat6 DNA binding activity by an oligonucleotide decoy blocks IL-4-driven T(H)2 cell response.
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Academic Article
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Selective disruption of interleukin 4 autocrine-regulated loop by a tyrosine kinase inhibitor restricts activity of T-helper 2 cells.
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Academic Article
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Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex.
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Academic Article
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Activation of receptor-associated tyrosine kinase JAK2 by prolactin.
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Academic Article
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Structural domains of interleukin-2 receptor beta critical for signal transduction: kinase association and nuclear complex-formation.
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Academic Article
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Isoproterenol-induced beta-2 adrenergic receptor activation negatively regulates interleukin-2 signaling.
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Academic Article
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Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways.
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Academic Article
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Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes.
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Academic Article
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Differential regulation of the Janus kinase-STAT pathway and biologic function of IL-13 in primary human NK and T cells: a comparative study with IL-4.
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Academic Article
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Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells.
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Academic Article
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Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts.
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Academic Article
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Tyrphostin AG490 selectively inhibits activation of the JAK3/STAT5/MAPK pathway and rejection of rat heart allografts.
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Academic Article
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Selective inhibition of IL-2 mRNA blocks allograft rejection by limiting T cell clonal expansion.
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Academic Article
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Targeting Jak3 for immune suppression and allograft acceptance.
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Academic Article
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PNU156804 inhibits Jak3 tyrosine kinase and rat heart allograft rejection.
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Academic Article
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The role of signals 1, 2, and 3 in induction of transplantation tolerance.
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Academic Article
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The role of Stat5 in the induction of regulatory T cells in transplantation tolerance.
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Academic Article
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Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.
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Academic Article
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Molecular actions of sirolimus: sirolimus and mTor.
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Academic Article
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Specific inhibition of Stat5a/b promotes apoptosis of IL-2-responsive primary and tumor-derived lymphoid cells.
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Academic Article
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Interleukin 4 regulates phosphorylation of serine 756 in the transactivation domain of Stat6. Roles for multiple phosphorylation sites and Stat6 function.
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Academic Article
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Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells.
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Academic Article
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Involvement of the ubiquitin-proteasome pathway in the degradation of nontyrosine kinase-type cytokine receptors of IL-9, IL-2, and erythropoietin.
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Academic Article
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Selective inhibition of IL-2 gene expression by IL-2 antisense oligonucleotides blocks heart allograft rejection.
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Academic Article
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Allochimeric class I MHC protein-induced tolerance by partial TCR engagement requires activation of both CTL4- and common gamma-chain-dependent cytokine signals.
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Academic Article
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Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.
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Academic Article
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New approaches to transplant immunosuppression.
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Academic Article
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Regulation of lymphoid cell apoptosis by Jaks and Stats.
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Academic Article
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Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit.
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Academic Article
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Allograft rejection requires STAT5a/b-regulated antiapoptotic activity in T cells but not B cells.
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Academic Article
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Janus tyrosine kinases and signal transducers and activators of transcription regulate critical functions of T cells in allograft rejection and transplantation tolerance.
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Academic Article
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Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.
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Academic Article
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Regulation of T cell homeostasis by JAKs and STATs.
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Academic Article
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The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells.
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Academic Article
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Immunocompromised tumor-bearing mice show a selective loss of STAT5a/b expression in T and B lymphocytes.
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Concept
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B-Lymphocytes
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Concept
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T-Lymphocytes, Helper-Inducer
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Concept
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Lymphocyte Activation
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Concept
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Lymphocytes
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Concept
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T-Lymphocytes
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Concept
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CD4-Positive T-Lymphocytes
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Concept
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Lymphocyte Subsets
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Concept
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Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
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Academic Article
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Molecular cloning of FKHRL1P2, a member of the developmentally regulated fork head domain transcription factor family.
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