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Saavedra, Harold

One or more keywords matched the following items that are connected to Saavedra, Harold

Item Type	Name
Academic Article	Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
Academic Article	Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model.
Academic Article	E2F activators signal and maintain centrosome amplification in breast cancer cells.
Academic Article	Nek2 and Plk4: prognostic markers, drivers of breast tumorigenesis and drug resistance.
Academic Article	Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosis.
Academic Article	Role of E2Fs and mitotic regulators controlled by E2Fs in the epithelial to mesenchymal transition.
Academic Article	Inactivation of E2F3 results in centrosome amplification.
Academic Article	Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.
Concept	Protein Kinases
Concept	Protein-Tyrosine Kinases
Concept	Cyclin-Dependent Kinases
Concept	Mitogen-Activated Protein Kinases
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	MAP Kinase Signaling System
Concept	MAP Kinase Kinase 1
Concept	Cyclin-Dependent Kinase Inhibitor p21
Concept	Cyclin-Dependent Kinase 2
Concept	Cyclin-Dependent Kinase 4
Academic Article	The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.
Academic Article	MAPK mediates RAS-induced chromosome instability.
Academic Article	The E2F1-3 transcription factors are essential for cellular proliferation.
Academic Article	The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2.
Academic Article	Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells.
Academic Article	Mitotic kinases as drivers of the epithelial-to-mesenchymal transition and as therapeutic targets against breast cancers.
Academic Article	The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells.
Academic Article	Ethnic and racial-specific differences in levels of centrosome-associated mitotic kinases, proliferative and epithelial-to-mesenchymal markers in breast cancers.

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Phosphotransferases

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