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Saavedra, Harold
One or more keywords matched the following items that are connected to
Saavedra, Harold
Item Type
Name
Academic Article
Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
Academic Article
Cdk4 and nek2 signal binucleation and centrosome amplification in a her2+ breast cancer model.
Academic Article
E2F activators signal and maintain centrosome amplification in breast cancer cells.
Academic Article
Nek2 and Plk4: prognostic markers, drivers of breast tumorigenesis and drug resistance.
Academic Article
Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosis.
Academic Article
Role of E2Fs and mitotic regulators controlled by E2Fs in the epithelial to mesenchymal transition.
Academic Article
Inactivation of E2F3 results in centrosome amplification.
Academic Article
Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation.
Concept
Protein Kinases
Concept
Protein-Tyrosine Kinases
Concept
Cyclin-Dependent Kinases
Concept
Mitogen-Activated Protein Kinases
Concept
Mitogen-Activated Protein Kinase Kinases
Concept
MAP Kinase Signaling System
Concept
MAP Kinase Kinase 1
Concept
Cyclin-Dependent Kinase Inhibitor p21
Concept
Cyclin-Dependent Kinase 2
Concept
Cyclin-Dependent Kinase 4
Academic Article
The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.
Academic Article
MAPK mediates RAS-induced chromosome instability.
Academic Article
The E2F1-3 transcription factors are essential for cellular proliferation.
Academic Article
The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2.
Academic Article
Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells.
Academic Article
Mitotic kinases as drivers of the epithelial-to-mesenchymal transition and as therapeutic targets against breast cancers.
Academic Article
The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells.
Academic Article
Ethnic and racial-specific differences in levels of centrosome-associated mitotic kinases, proliferative and epithelial-to-mesenchymal markers in breast cancers.
Grant
Targeting centrosome-mitotic kinases as a novel therapeutic approach against breast cancers in Hispanic/Latinas.
Academic Article
Mitotic kinases are emerging therapeutic targets against metastatic breast cancer.
Search Criteria
Cyclic GMP Dependent Protein Kinases