"Receptors, Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
| Descriptor ID |
D054411
|
| MeSH Number(s) |
D12.776.543.750.650.500
|
| Concept/Terms |
Receptors, Leptin- Receptors, Leptin
- Leptin-Binding Protein
- Leptin Binding Protein
- Receptor, Leptin
- Leptin Receptor
- Antigens, CD295
- LEPR Protein
- OB Receptor
- Receptor, OB
- CD295 Antigens
- Leptin Receptors
OBRb Receptor- OBRb Receptor
- Receptor, OBRb
- Leptin Receptor, Large Isoform
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Leptin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leptin".
This graph shows the total number of publications written about "Receptors, Leptin" by people in this website by year, and whether "Receptors, Leptin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Leptin" by people in Profiles.
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Lipsey CC, Harbuzariu A, Robey RW, Huff LM, Gottesman MM, Gonzalez-Perez RR. Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer. Int J Mol Sci. 2020 May 27; 21(11).
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Ramirez O, Garza KM. Leptin deficiency in vivo enhances the ability of splenic dendritic cells to activate T cells. Int Immunol. 2014 Nov; 26(11):627-36.
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Tsai PJ, Davis J, Bryant-Greenwood G. Systemic and placental leptin and its receptors in pregnancies associated with obesity. Reprod Sci. 2015 Feb; 22(2):189-97.
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Kumar M, Roe K, Nerurkar PV, Orillo B, Thompson KS, Verma S, Nerurkar VR. Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus. J Neuroinflammation. 2014 Apr 21; 11:80.
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Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. J Neurochem. 2014 Jan; 128(1):162-72.
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Newman G, Gonzalez-Perez RR. Leptin-cytokine crosstalk in breast cancer. Mol Cell Endocrinol. 2014 Jan 25; 382(1):570-582.
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Guo S, Liu M, Wang G, Torroella-Kouri M, Gonzalez-Perez RR. Oncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cells. Biochim Biophys Acta. 2012 Apr; 1825(2):207-22.
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Abdennebi-Najar L, Desai M, Han G, Casillas E, Jean D, Arieh G, Ross MG. Basal, endogenous leptin is metabolically active in newborn rat pups. J Matern Fetal Neonatal Med. 2011 Dec; 24(12):1486-91.
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Beales IL, Ogunwobi OO. Leptin synergistically enhances the anti-apoptotic and growth-promoting effects of acid in OE33 oesophageal adenocarcinoma cells in culture. Mol Cell Endocrinol. 2007 Aug 15; 274(1-2):60-8.
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Desai M, Gayle D, Han G, Ross MG. Programmed hyperphagia due to reduced anorexigenic mechanisms in intrauterine growth-restricted offspring. Reprod Sci. 2007 May; 14(4):329-37.