"Smad2 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor-regulated smad protein that undergoes PHOSPHORYLATION by ACTIVIN RECEPTORS, TYPE I. It regulates TRANSFORMING GROWTH FACTOR BETA and ACTIVIN signaling.
| Descriptor ID |
D051899
|
| MeSH Number(s) |
D12.644.360.024.334.500.200 D12.776.157.057.170.500.200 D12.776.476.024.428.500.200 D12.776.744.741.750 D12.776.930.806.500.200
|
| Concept/Terms |
Smad2 Protein- Smad2 Protein
- MAD-Related 2 Protein
- MAD Related 2 Protein
- MADR2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Smad2 Protein".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Adaptor Proteins, Signal Transducing [D12.644.360.024]
- Smad Proteins [D12.644.360.024.334]
- Smad Proteins, Receptor-Regulated [D12.644.360.024.334.500]
- Smad2 Protein [D12.644.360.024.334.500.200]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Adaptor Proteins, Signal Transducing [D12.776.157.057]
- Smad Proteins [D12.776.157.057.170]
- Smad Proteins, Receptor-Regulated [D12.776.157.057.170.500]
- Smad2 Protein [D12.776.157.057.170.500.200]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Adaptor Proteins, Signal Transducing [D12.776.476.024]
- Smad Proteins [D12.776.476.024.428]
- Smad Proteins, Receptor-Regulated [D12.776.476.024.428.500]
- Smad2 Protein [D12.776.476.024.428.500.200]
- Phosphoproteins [D12.776.744]
- Smad Proteins, Receptor-Regulated [D12.776.744.741]
- Smad2 Protein [D12.776.744.741.750]
- Transcription Factors [D12.776.930]
- Smad Proteins [D12.776.930.806]
- Smad Proteins, Receptor-Regulated [D12.776.930.806.500]
- Smad2 Protein [D12.776.930.806.500.200]
Below are MeSH descriptors whose meaning is more specific than "Smad2 Protein".
This graph shows the total number of publications written about "Smad2 Protein" by people in this website by year, and whether "Smad2 Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 2 | 0 | 2 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Smad2 Protein" by people in Profiles.
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Wu M, Feng Y, Ye GX, Han YC, Wang SS, Ni HF, Wang FM, Gao M, Lv LL, Liu BC. Calcium-sensing receptor activation attenuates collagen expression in renal proximal tubular epithelial cells. Am J Physiol Renal Physiol. 2019 05 01; 316(5):F1006-F1015.
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Yoshimoto T, Fujita T, Kajiya M, Ouhara K, Matsuda S, Komatsuzawa H, Shiba H, Kurihara H. Aggregatibacter actinomycetemcomitans outer membrane protein 29 (Omp29) induces TGF-?-regulated apoptosis signal in human gingival epithelial cells via fibronectin/integrin?1/FAK cascade. Cell Microbiol. 2016 Dec; 18(12):1723-1738.
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Sun Z, Schriewer J, Tang M, Marlin J, Taylor F, Shohet RV, Konorev EA. The TGF-? pathway mediates doxorubicin effects on cardiac endothelial cells. J Mol Cell Cardiol. 2016 Jan; 90:129-38.
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Yoshimoto T, Fujita T, Kajiya M, Matsuda S, Ouhara K, Shiba H, Kurihara H. Involvement of smad2 and Erk/Akt cascade in TGF-?1-induced apoptosis in human gingival epithelial cells. Cytokine. 2015 Sep; 75(1):165-73.
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Kumar V, Maurya VK, Joshi A, Meeran SM, Jha RK. Integrin beta 8 (ITGB8) regulates embryo implantation potentially via controlling the activity of TGF-B1 in mice. Biol Reprod. 2015 Apr; 92(4):109.
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Fujita T, Alotaibi M, Kitase Y, Kota Y, Ouhara K, Kurihara H, Shuler CF. Smad2 is involved in the apoptosis of murine gingival junctional epithelium associated with inhibition of Bcl-2. Arch Oral Biol. 2012 Nov; 57(11):1567-73.
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Vo BT, Cody B, Cao Y, Khan SA. Differential role of Sloan-Kettering Institute (Ski) protein in Nodal and transforming growth factor-beta (TGF-?)-induced Smad signaling in prostate cancer cells. Carcinogenesis. 2012 Nov; 33(11):2054-64.
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Miyasato SK, Loeffler J, Shohet R, Zhang J, Lindsey M, Le Saux CJ. Caveolin-1 modulates TGF-?1 signaling in cardiac remodeling. Matrix Biol. 2011 Jun; 30(5-6):318-29.
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Vo BT, Khan SA. Expression of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration. Prostate. 2011 Jul; 71(10):1084-96.
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Lee HG, Ueda M, Zhu X, Perry G, Smith MA. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? J Neurosci Res. 2006 Dec; 84(8):1856-61.