"Dystroglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dystrophin-associated proteins that play role in the formation of a transmembrane link between laminin-2 and DYSTROPHIN. Both the alpha and the beta subtypes of dystroglycan originate via POST-TRANSLATIONAL PROTEIN PROCESSING of a single precursor protein.
| Descriptor ID |
D049030
|
| MeSH Number(s) |
D12.776.210.500.410.500 D12.776.220.362.249 D12.776.543.268.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Dystroglycans".
Below are MeSH descriptors whose meaning is more specific than "Dystroglycans".
This graph shows the total number of publications written about "Dystroglycans" by people in this website by year, and whether "Dystroglycans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dystroglycans" by people in Profiles.
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Zhou YW, Munoz J, Jiang D, Jarrett HW. Laminin-a1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-?B transcription factors but also has adverse effects. Am J Physiol Cell Physiol. 2012 Mar 15; 302(6):C902-14.
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Munoz J, Zhou Y, Jarrett HW. LG4-5 domains of laminin-211 binds alpha-dystroglycan to allow myotube attachment and prevent anoikis. J Cell Physiol. 2010 Jan; 222(1):111-9.
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Zhou YW, Thomason DB, Gullberg D, Jarrett HW. Binding of laminin alpha1-chain LG4-5 domain to alpha-dystroglycan causes tyrosine phosphorylation of syntrophin to initiate Rac1 signaling. Biochemistry. 2006 Feb 21; 45(7):2042-52.
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Chockalingam PS, Cholera R, Oak SA, Zheng Y, Jarrett HW, Thomason DB. Dystrophin-glycoprotein complex and Ras and Rho GTPase signaling are altered in muscle atrophy. Am J Physiol Cell Physiol. 2002 Aug; 283(2):C500-11.
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Oak SA, Russo K, Petrucci TC, Jarrett HW. Mouse alpha1-syntrophin binding to Grb2: further evidence of a role for syntrophin in cell signaling. Biochemistry. 2001 Sep 18; 40(37):11270-8.