"Chromosome Breakage" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of chromosomal aberration involving DNA BREAKS. Chromosome breakage can result in CHROMOSOMAL TRANSLOCATION; CHROMOSOME INVERSION; or SEQUENCE DELETION.
| Descriptor ID |
D019457
|
| MeSH Number(s) |
C23.550.210.170 G05.200.210.170 G05.365.590.175.175
|
| Concept/Terms |
Chromosome Breakage- Chromosome Breakage
- Breakage, Chromosome
- Breakages, Chromosome
- Chromosome Breakages
- Chromosomal Breakage
- Breakage, Chromosomal
- Breakages, Chromosomal
- Chromosomal Breakages
Chromosome Breaks- Chromosome Breaks
- Break, Chromosome
- Breaks, Chromosome
- Chromosome Break
- Chromosomal Breaks
- Break, Chromosomal
- Breaks, Chromosomal
- Chromosomal Break
|
Below are MeSH descriptors whose meaning is more general than "Chromosome Breakage".
Below are MeSH descriptors whose meaning is more specific than "Chromosome Breakage".
This graph shows the total number of publications written about "Chromosome Breakage" by people in this website by year, and whether "Chromosome Breakage" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Chromosome Breakage" by people in Profiles.
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Russell B, Bhattacharyya S, Keirsey J, Sandy A, Grierson P, Perchiniak E, Kavecansky J, Acharya S, Groden J. Chromosome breakage is regulated by the interaction of the BLM helicase and topoisomerase IIalpha. Cancer Res. 2011 Jan 15; 71(2):561-71.
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Yamauchi Y, Riel JM, Stoytcheva Z, Burgoyne PS, Ward MA. Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damage. Genome Biol. 2010; 11(6):R66.
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Kulharya AS, Flannery DB, Norris K, Lovell C, Levy B, Velagaleti GV. Fine mapping of breakpoints in two unrelated patients with rare overlapping interstitial deletions of 9q with mild dysmorphic features. Am J Med Genet A. 2008 Sep 01; 146A(17):2234-41.
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Yamauchi Y, Doe B, Ajduk A, Ward MA. Genomic DNA damage in mouse transgenesis. Biol Reprod. 2007 Nov; 77(5):803-12.
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Yamauchi Y, Ajduk A, Riel JM, Ward MA. Ejaculated and epididymal mouse spermatozoa are different in their susceptibility to nuclease-dependent DNA damage and in their nuclease activity. Biol Reprod. 2007 Oct; 77(4):636-47.
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Bredemeyer AL, Sharma GG, Huang CY, Helmink BA, Walker LM, Khor KC, Nuskey B, Sullivan KE, Pandita TK, Bassing CH, Sleckman BP. ATM stabilizes DNA double-strand-break complexes during V(D)J recombination. Nature. 2006 Jul 27; 442(7101):466-70.
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Szczygiel MA, Moisyadi S, Ward WS. Expression of foreign DNA is associated with paternal chromosome degradation in intracytoplasmic sperm injection-mediated transgenesis in the mouse. Biol Reprod. 2003 May; 68(5):1903-10.
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Garibay-Tupas JL, Csisz?r K, Fox M, Povey S, Bryant-Greenwood GD. Analysis of the 5'-upstream regions of the human relaxin H1 and H2 genes and their chromosomal localization on chromosome 9p24.1 by radiation hybrid and breakpoint mapping. J Mol Endocrinol. 1999 Dec; 23(3):355-65.