Sex-Determining Region Y Protein
"Sex-Determining Region Y Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that plays an essential role in the development of the TESTES. It is encoded by a gene on the Y chromosome and contains a specific HMG-BOX DOMAIN that is found within members of the SOX family of transcription factors.
| Descriptor ID |
D051876
|
| MeSH Number(s) |
D12.776.260.719.049 D12.776.660.235.400.750.049 D12.776.664.235.400.750.049 D12.776.930.823.049
|
| Concept/Terms |
Sex-Determining Region Y Protein- Sex-Determining Region Y Protein
- Sex Determining Region Y Protein
- Testis-Determining Factor
- Testis Determining Factor
- SRY Sex-Determining Region Protein
- SRY Sex Determining Region Protein
|
Below are MeSH descriptors whose meaning is more general than "Sex-Determining Region Y Protein".
Below are MeSH descriptors whose meaning is more specific than "Sex-Determining Region Y Protein".
This graph shows the total number of publications written about "Sex-Determining Region Y Protein" by people in this website by year, and whether "Sex-Determining Region Y Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sex-Determining Region Y Protein" by people in Profiles.
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Yamauchi Y, Riel JM, Ruthig VA, Ortega EA, Mitchell MJ, Ward MA. Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction. Science. 2016 Jan 29; 351(6272):514-6.
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Yamauchi Y, Riel JM, Ruthig V, Ward MA. Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Formation and Function in Assisted Fertilization. PLoS Genet. 2015 Dec; 11(12):e1005476.
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Ortega EA, Ruthig VA, Ward MA. Sry-Independent Overexpression of Sox9 Supports Spermatogenesis and Fertility in the Mouse. Biol Reprod. 2015 Dec; 93(6):141.
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Yamauchi Y, Riel JM, Stoytcheva Z, Ward MA. Two Y genes can replace the entire Y chromosome for assisted reproduction in the mouse. Science. 2014 Jan 03; 343(6166):69-72.
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Smith CL, Baek ST, Sung CY, Tallquist MD. Epicardial-derived cell epithelial-to-mesenchymal transition and fate specification require PDGF receptor signaling. Circ Res. 2011 Jun 10; 108(12):e15-26.