"Idazoxan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A benzodioxane-linked imidazole that has alpha-2 adrenoceptor antagonist activity.
| Descriptor ID |
D019329
|
| MeSH Number(s) |
D03.383.129.308.428 D03.383.188.425 D03.633.100.355
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Idazoxan".
Below are MeSH descriptors whose meaning is more specific than "Idazoxan".
This graph shows the total number of publications written about "Idazoxan" by people in this website by year, and whether "Idazoxan" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Idazoxan" by people in Profiles.
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Jim?nez-Rivera CA, Feliu-Mojer M, V?zquez-Torres R. Alpha-noradrenergic receptors modulate the development and expression of cocaine sensitization. Ann N Y Acad Sci. 2006 Aug; 1074:390-402.
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Piletz JE, Ivanov TR, Sharp JD, Ernsberger P, Chang CH, Pickard RT, Gold G, Roth B, Zhu H, Jones JC, Baldwin J, Reis DJ. Imidazoline receptor antisera-selected (IRAS) cDNA: cloning and characterization. DNA Cell Biol. 2000 Jun; 19(6):319-29.
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Zhang KM, Wang XM, Peterson AM, Chen WY, Mokha SS. alpha2-adrenoceptors modulate NMDA-evoked responses of neurons in superficial and deeper dorsal horn of the medulla. J Neurophysiol. 1998 Oct; 80(4):2210-4.
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Ivanov TR, Feng Y, Wang H, Regunathan S, Reis DJ, Chikkala DN, Gupta P, Jones JC, Piletz JE. Imidazoline receptor proteins are regulated in platelet-precursor MEG-01 cells by agonists and antagonists. J Psychiatr Res. 1998 Mar-Apr; 32(2):65-79.
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Zhu H, Paul IA, McNamara M, Redmond A, Nowak G, Piletz JE. Chronic imipramine treatment upregulates IR2-imidazoline receptive sites in rat brain. Neurochem Int. 1997 Jan; 30(1):101-7.
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Piletz JE, Sletten K. Nonadrenergic imidazoline binding sites on human platelets. J Pharmacol Exp Ther. 1993 Dec; 267(3):1493-502.
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Hamilton CA, Yakubu MA, Jardine E, Reid JL. Imidazole binding sites in rabbit kidney and forebrain membranes. J Auton Pharmacol. 1991 Aug; 11(4):277-83.
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Yakubu MA, Deighton NM, Hamilton CA, Reid JL. Differences in the regulation of [3H]idazoxan and [3H]yohimbine binding sites in the rabbit. Eur J Pharmacol. 1990 Feb 13; 176(3):305-11.
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Yakubu MA, Hamilton CA, Howie CA, Reid JL. Idazoxan and brain alpha 2-adrenoceptors in the rabbit. Brain Res. 1988 Nov 01; 463(2):289-95.
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Hamilton CA, Reid JL, Yakubu MA. [3H]yohimbine and [3H]idazoxan bind to different sites on rabbit forebrain and kidney membranes. Eur J Pharmacol. 1988 Feb 09; 146(2-3):345-8.