"Clonidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
| Descriptor ID |
D003000
|
| MeSH Number(s) |
D03.383.129.308.436.500
|
| Concept/Terms |
Clonidine Hydrochloride- Clonidine Hydrochloride
- Hydrochloride, Clonidine
- Clonidine Monohydrochloride
- Monohydrochloride, Clonidine
|
Below are MeSH descriptors whose meaning is more general than "Clonidine".
Below are MeSH descriptors whose meaning is more specific than "Clonidine".
This graph shows the total number of publications written about "Clonidine" by people in this website by year, and whether "Clonidine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 2 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2002 | 3 | 0 | 3 |
| 2003 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 3 | 1 | 4 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Clonidine" by people in Profiles.
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Pramar YV, Mandal TK, Bostanian LA, Johnson J, Graves RA. Physicochemical and Microbiological Stability of Compounded Clonidine Hydrochloride Oral Liquid Dosage Forms in PCCA Base, SuspendIt?. Int J Pharm Compd. 2024 Jul-Aug; 28(4):334-343.
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Nag S, Mokha SS. Activation of the trigeminal a2-adrenoceptor produces sex-specific, estrogen dependent thermal antinociception and antihyperalgesia using an operant pain assay in the rat. Behav Brain Res. 2016 11 01; 314:152-8.
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Nag S, Mokha SS. Activation of a Gq-coupled membrane estrogen receptor rapidly attenuates a2-adrenoceptor-induced antinociception via an ERK I/II-dependent, non-genomic mechanism in the female rat. Neuroscience. 2014 May 16; 267:122-34.
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Jim?nez-Rivera CA, Figueroa J, V?zquez-Torres R, V?lez-Hernandez ME, Schwarz D, Vel?squez-Martinez MC, Arencibia-Albite F. Presynaptic inhibition of glutamate transmission by a2 receptors in the VTA. Eur J Neurosci. 2012 May; 35(9):1406-15.
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Inyushin MU, Arencibia-Albite F, V?zquez-Torres R, V?lez-Hern?ndez ME, Jim?nez-Rivera CA. Alpha-2 noradrenergic receptor activation inhibits the hyperpolarization-activated cation current (Ih) in neurons of the ventral tegmental area. Neuroscience. 2010 May 05; 167(2):287-97.
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Nag S, Mokha SS. Testosterone is essential for alpha(2)-adrenoceptor-induced antinociception in the trigeminal region of the male rat. Neurosci Lett. 2009 Dec 18; 467(1):48-52.
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Nag S, Wang Q, Limbird LE, Mokha SS. Knockout of spinophilin, an endogenous antagonist of arrestin-dependent alpha2-adrenoceptor functions, enhances receptor-mediated antinociception yet does not eliminate sex-related differences. Behav Brain Res. 2009 Feb 11; 197(2):457-61.
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Thompson AD, Angelotti T, Nag S, Mokha SS. Sex-specific modulation of spinal nociception by alpha2-adrenoceptors: differential regulation by estrogen and testosterone. Neuroscience. 2008 Jun 02; 153(4):1268-77.
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Palumbo DR, Sallee FR, Pelham WE, Bukstein OG, Daviss WB, McDERMOTT MP. Clonidine for attention-deficit/hyperactivity disorder: I. Efficacy and tolerability outcomes. J Am Acad Child Adolesc Psychiatry. 2008 Feb; 47(2):180-188.
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Daviss WB, Patel NC, Robb AS, McDERMOTT MP, Bukstein OG, Pelham WE, Palumbo D, Harris P, Sallee FR. Clonidine for attention-deficit/hyperactivity disorder: II. ECG changes and adverse events analysis. J Am Acad Child Adolesc Psychiatry. 2008 Feb; 47(2):189-198.