Isoquinolines

"Isoquinolines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of compounds with the heterocyclic ring structure of benzo(c)pyridine. The ring structure is characteristic of the group of opium alkaloids such as papaverine. (From Stedman, 25th ed)

Descriptor ID	D007546
MeSH Number(s)	D03.633.100.531
Concept/Terms	Isoquinolines Isoquinolines

Below are MeSH descriptors whose meaning is more general than "Isoquinolines".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Isoquinolines [D03.633.100.531]

Below are MeSH descriptors whose meaning is related to "Isoquinolines".

Below are MeSH descriptors whose meaning is more specific than "Isoquinolines".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Isoquinolines" by people in this website by year, and whether "Isoquinolines" was a major or minor topic of these publications.

Bar chart showing 34 publications over 21 distinct years, with a maximum of 4 publications in 2012 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	1	2
2002	1	1	2
2003	0	1	1
2005	1	1	2
2006	0	1	1
2007	1	0	1
2008	2	0	2
2009	1	0	1
2010	2	0	2
2011	0	1	1
2012	1	3	4
2013	0	1	1
2015	2	0	2
2016	1	0	1
2017	1	0	1
2019	4	0	4
2020	0	2	2
2021	1	0	1
2022	0	1	1
2024	0	1	1
2025	0	1	1

Below are the most recent publications written about "Isoquinolines" by people in Profiles.

Okpattah D, Karki A, Pillarsetty NVK, Harding WW. Synthesis and evaluation of aporphinoid 5-HT7AR ligands as inhibitors of PC3 prostate cancer cell growth. Bioorg Med Chem Lett. 2025 Dec 01; 128:130328.

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Mori LP, Corley MJ, McAuley AT, Pang A, Venables T, Ndhlovu LC, Pipkin ME, Valente ST. Transcriptional and methylation outcomes of didehydro-cortistatin A use in HIV-1-infected CD4+ T cells. Life Sci Alliance. 2024 10; 7(10).

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Messeha SS, Noel S, Zarmouh NO, Womble T, Latinwo LM, Soliman KFA. Involvement of AKT/PI3K Pathway in Sanguinarine's Induced Apoptosis and Cell Cycle Arrest in Triple-negative Breast Cancer Cells. Cancer Genomics Proteomics. 2023 Jul-Aug; 20(4):323-342.

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Getachew B, Csoka AB, Copeland RL, Manaye KF, Tizabi Y. Dihydromyricetin Protects Against Salsolinol-Induced Toxicity in Dopaminergic Cell Line: Implication for Parkinson's Disease. Neurotox Res. 2023 Apr; 41(2):141-148.

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Messeha SS, Zarmouh NO, Antonie L, Soliman KFA. Sanguinarine Inhibition of TNF-a-Induced CCL2, IKBKE/NF-?B/ERK1/2 Signaling Pathway, and Cell Migration in Human Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2022 Jul 28; 23(15).

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Gangapuram M, Mazzio EA, Redda KK, Soliman KFA. Transcriptome Profile Analysis of Triple-Negative Breast Cancer Cells in Response to a Novel Cytostatic Tetrahydroisoquinoline Compared to Paclitaxel. Int J Mol Sci. 2021 Jul 19; 22(14).

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Wan S, Cao S, Wang X, Zhou Y, Yan W, Gu X, Wu TC, Pang X. Generation and preliminary characterization of vertebrate-specific replication-defective Zika virus. Virology. 2021 01 02; 552:73-82.

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Salehi S, Kashfi K, Manaheji H, Haghparast A. Chemical stimulation of the lateral hypothalamus induces antiallodynic and anti-thermal hyperalgesic effects in animal model of neuropathic pain: Involvement of orexin receptors in the spinal cord. Brain Res. 2020 04 01; 1732:146674.

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Chen N, Hao C, Peng X, Lin H, Yin A, Hao L, Tao Y, Liang X, Liu Z, Xing C, Chen J, Luo L, Zuo L, Liao Y, Liu BC, Leong R, Wang C, Liu C, Neff T, Szczech L, Yu KP. Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis. N Engl J Med. 2019 09 12; 381(11):1001-1010.

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Chen N, Hao C, Liu BC, Lin H, Wang C, Xing C, Liang X, Jiang G, Liu Z, Li X, Zuo L, Luo L, Wang J, Zhao MH, Liu Z, Cai GY, Hao L, Leong R, Wang C, Liu C, Neff T, Szczech L, Yu KP. Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis. N Engl J Med. 2019 09 12; 381(11):1011-1022.

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