"Naphthalimides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds with three fused rings that appear like a naphthalene fused to piperidone or like a benz(de)isoquinoline-1,3-dione (not to be confused with BENZYLISOQUINOLINES which have a methyl separating the naphthyl from the benzyl rings). Members are CYTOTOXINS.
| Descriptor ID |
D053644
|
| MeSH Number(s) |
D02.478.480 D03.383.621.808.612 D03.633.100.531.460 D04.615.638.596
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Naphthalimides".
Below are MeSH descriptors whose meaning is more specific than "Naphthalimides".
This graph shows the total number of publications written about "Naphthalimides" by people in this website by year, and whether "Naphthalimides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Naphthalimides" by people in Profiles.
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Najar MA, Aravind A, Dagamajalu S, Sidransky D, Ashktorab H, Smoot DT, Gowda H, Prasad TSK, Modi PK, Chatterjee A. Hyperactivation of MEK/ERK pathway by Ca2+ /calmodulin-dependent protein kinase kinase 2?promotes cellular proliferation by activating cyclin-dependent kinases?and minichromosome maintenance protein?in gastric cancer cells. Mol Carcinog. 2021 11; 60(11):769-783.
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Kumar NP, Nekkanti S, Sujana Kumari S, Sharma P, Shankaraiah N. Design and synthesis of 1,2,3-triazolo-phenanthrene hybrids as cytotoxic agents. Bioorg Med Chem Lett. 2017 06 01; 27(11):2369-2376.
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Wang H, Silva AJ, Benitez JA. 3-Amino 1,8-naphthalimide, a structural analog of the anti-cholera drug virstatin inhibits chemically-biased swimming and swarming motility in vibrios. Microbes Infect. 2017 06; 19(6):370-375.
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Childers BM, Cao X, Weber GG, Demeler B, Hart PJ, Klose KE. N-terminal residues of the Vibrio cholerae virulence regulatory protein ToxT involved in dimerization and modulation by fatty acids. J Biol Chem. 2011 Aug 12; 286(32):28644-55.