"Saquinavir" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits CYTOCHROME P-450 CYP3A.
| Descriptor ID |
D019258
|
| MeSH Number(s) |
D03.633.100.531.770 D03.633.100.810.900
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Saquinavir".
Below are MeSH descriptors whose meaning is more specific than "Saquinavir".
This graph shows the total number of publications written about "Saquinavir" by people in this website by year, and whether "Saquinavir" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Saquinavir" by people in Profiles.
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S?nchez Mdel C, L?pez P, V?lez R, Yamamura Y. P-glycoprotein expression in HTLV-III cells after treatment with HIV-1 protease inhibitors. Ethn Dis. 2008; 18(2 Suppl 2):S2-60-4.
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Zorrilla CD, Van Dyke R, Bardeguez A, Acosta EP, Smith B, Hughes MD, Huang S, Watts DH, Heckman B, Jim?nez E, McSherry G, Mofenson L. Clinical response and tolerability to and safety of saquinavir with low-dose ritonavir in human immunodeficiency virus type 1-infected mothers and their infants. Antimicrob Agents Chemother. 2007 Jun; 51(6):2208-10.
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Acosta EP, Bardeguez A, Zorrilla CD, Van Dyke R, Hughes MD, Huang S, Pompeo L, Stek AM, Pitt J, Watts DH, Smith E, Jim?nez E, Mofenson L. Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women. Antimicrob Agents Chemother. 2004 Feb; 48(2):430-6.