"PC12 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.
| Descriptor ID |
D016716
|
| MeSH Number(s) |
A11.251.210.190.750 A11.251.860.180.750 A11.299.500
|
| Concept/Terms |
PC12 Cells- PC12 Cells
- PC12 Cell
- Pheochromocytoma Cell Line
- Cell Line, Pheochromocytoma
- Cell Lines, Pheochromocytoma
- Pheochromocytoma Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "PC12 Cells".
Below are MeSH descriptors whose meaning is more specific than "PC12 Cells".
This graph shows the total number of publications written about "PC12 Cells" by people in this website by year, and whether "PC12 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 3 | 3 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 5 | 5 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 5 | 5 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 3 | 3 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "PC12 Cells" by people in Profiles.
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James NG, Malik S, Sanstrum BJ, Rh?aume C, Broide RS, Jameson DM, Brideau-Andersen A, Jacky BS. Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay. Sci Rep. 2021 04 09; 11(1):7832.
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Sierra-Fonseca JA, Miranda M, Das S, Roychowdhury S. The ?? subunit of heterotrimeric G proteins interacts with actin filaments during neuronal differentiation. Biochem Biophys Res Commun. 2021 04 16; 549:98-104.
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Gamdzyk M, Doycheva DM, Kang R, Tang H, Travis ZD, Tang J, Zhang JH. GW0742 activates miR-17-5p and inhibits TXNIP/NLRP3-mediated inflammation after hypoxic-ischaemic injury in rats and in PC12 cells. J Cell Mol Med. 2020 11; 24(21):12318-12330.
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Jones PM, Mazzio E, Soliman K, George AM. In Silico Investigation of the Binding of MCoTI-II Plant Defense Knottin to the ?-NGF Serine Protease of the 7S Nerve Growth Factor Complex and Biological Activity of Its NGF Mimetic Properties. J Phys Chem B. 2019 10 31; 123(43):9104-9110.
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Sierra-Fonseca JA, Bracamontes C, Saldecke J, Das S, Roychowdhury S. Activation of ?- and a2-adrenergic receptors stimulate tubulin polymerization and promote the association of G?? with microtubules in cultured NIH3T3 cells. Biochem Biophys Res Commun. 2018 09 03; 503(1):102-108.
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Badisa RB, Batton CS, Mazzio E, Grant SC, Goodman CB. Identification of biochemical and cytotoxic markers in cocaine treated PC12 cells. Sci Rep. 2018 02 09; 8(1):2710.
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Omtri RS, Thompson KJ, Tang X, Gali CC, Panzenboeck U, Davidson MW, Kalari KR, Kandimalla KK. Differential Effects of Alzheimer's Disease A?40 and 42 on Endocytosis and Intraneuronal Trafficking. Neuroscience. 2018 03 01; 373:159-168.
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Arvaniti M, Jensen MM, Soni N, Wang H, Klein AB, Thiriet N, Pinborg LH, Muldoon PP, Wienecke J, Imad Damaj M, Kohlmeier KA, Gondr?-Lewis MC, Mikkelsen JD, Thomsen MS. Functional interaction between Lypd6 and nicotinic acetylcholine receptors. J Neurochem. 2016 09; 138(6):806-20.
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Li X, Zhao S, Hu H, Liu YM. A microchip electrophoresis-mass spectrometric platform with double cell lysis nano-electrodes for automated single cell analysis. J Chromatogr A. 2016 Jun 17; 1451:156-163.
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Li X, Hu H, Zhao S, Liu YM. Microfluidic Platform with In-Chip Electrophoresis Coupled to Mass Spectrometry for Monitoring Neurochemical Release from Nerve Cells. Anal Chem. 2016 05 17; 88(10):5338-44.