HL-60 Cells

"HL-60 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)

Descriptor ID	D018922
MeSH Number(s)	A11.251.210.190.465 A11.251.860.180.465 A11.627.340.360.500
Concept/Terms	HL-60 Cells HL-60 Cells HL 60 Cells HL-60 Cell HL60 Cells Cell, HL60 Cells, HL60 HL60 Cell

Below are MeSH descriptors whose meaning is more general than "HL-60 Cells".

Anatomy [A]
Cells [A11]
Cells, Cultured [A11.251]
Cell Line [A11.251.210]
Cell Line, Tumor [A11.251.210.190]
HL-60 Cells [A11.251.210.190.465]
Tumor Cells, Cultured [A11.251.860]
Cell Line, Tumor [A11.251.860.180]
HL-60 Cells [A11.251.860.180.465]
Myeloid Cells [A11.627]
Granulocytes [A11.627.340]
Granulocyte Precursor Cells [A11.627.340.360]
HL-60 Cells [A11.627.340.360.500]

Below are MeSH descriptors whose meaning is related to "HL-60 Cells".

Below are MeSH descriptors whose meaning is more specific than "HL-60 Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "HL-60 Cells" by people in this website by year, and whether "HL-60 Cells" was a major or minor topic of these publications.

Bar chart showing 28 publications over 15 distinct years, with a maximum of 4 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2000	0	1	1
2001	0	1	1
2002	0	1	1
2003	0	1	1
2004	0	3	3
2006	0	2	2
2007	1	1	2
2008	0	2	2
2009	0	2	2
2010	0	4	4
2014	0	3	3
2015	0	3	3
2016	0	1	1
2020	0	1	1

Below are the most recent publications written about "HL-60 Cells" by people in Profiles.

Emadi A, Kapadia B, Bollino D, Bhandary B, Baer MR, Niyongere S, Strovel ET, Kaizer H, Chang E, Choi EY, Ma X, Tighe KM, Carter-Cooper B, Moses BS, Civin CI, Mahurkar A, Shetty AC, Gartenhaus RB, Kamangar F, Lapidus RG. Venetoclax and pegcrisantaspase for complex karyotype acute myeloid leukemia. Leukemia. 2021 07; 35(7):1907-1924.

View in: PubMed
Pulliam SR, Pellom ST, Shanker A, Adunyah SE. Butyrate regulates the expression of inflammatory and chemotactic cytokines in human acute leukemic cells during apoptosis. Cytokine. 2016 08; 84:74-87.

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Yedjou CG, Tchounwou HM, Tchounwou PB. DNA Damage, Cell Cycle Arrest, and Apoptosis Induction Caused by Lead in Human Leukemia Cells. Int J Environ Res Public Health. 2015 Dec 22; 13(1):ijerph13010056.

View in: PubMed
Tyagi M, Iordanskiy S, Ammosova T, Kumari N, Smith K, Breuer D, Ilatovskiy AV, Kont YS, Ivanov A, ?ren A, Kovalskyy D, Petukhov M, Kashanchi F, Nekhai S. Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1. Retrovirology. 2015 Jul 16; 12:63.

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de Necochea-Campion R, Diaz Osterman CJ, Hsu HW, Fan J, Mirshahidi S, Wall NR, Chen CS. AML sensitivity to YM155 is modulated through AKT and Mcl-1. Cancer Lett. 2015 Sep 28; 366(1):44-51.

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Kumar S, Yedjou CG, Tchounwou PB. Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells. J Exp Clin Cancer Res. 2014 May 16; 33:42.

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Santiago-Vazquez Y, Das S, Das U, Robles-Escajeda E, Ortega NM, Lema C, Varela-Ram?rez A, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity. Eur J Med Chem. 2014 Apr 22; 77:315-22.

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Ghoneum M, Gimzewski J. Apoptotic effect of a novel kefir product, PFT, on multidrug-resistant myeloid leukemia cells via a hole-piercing mechanism. Int J Oncol. 2014 Mar; 44(3):830-7.

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Dikmen M, Canturk Z, Ozturk Y, Tunali Y. Investigation of the apoptotic effect of curcumin in human leukemia HL-60 cells by using flow cytometry. Cancer Biother Radiopharm. 2010 Dec; 25(6):749-55.

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Yedjou C, Tchounwou P, Jenkins J, McMurray R. Basic mechanisms of arsenic trioxide (ATO)-induced apoptosis in human leukemia (HL-60) cells. J Hematol Oncol. 2010 Aug 26; 3:28.

View in: PubMed

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