"Papaverine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
| Descriptor ID |
D010208
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| MeSH Number(s) |
D03.132.098.666 D03.132.577.750 D03.633.100.531.085.666
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Papaverine".
Below are MeSH descriptors whose meaning is more specific than "Papaverine".
This graph shows the total number of publications written about "Papaverine" by people in this website by year, and whether "Papaverine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Papaverine" by people in Profiles.
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Davila HH, Rajfer J, Gonzalez-Cadavid NF. Corporal veno-occlusive dysfunction in aging rats: evaluation by cavernosometry and cavernosography. Urology. 2004 Dec; 64(6):1261-6.
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Ohia SE, Boyle FC. Involvement of prostaglandins in the inhibitory response of adrenoceptor agonists in the rat isolated uterus. Gen Pharmacol. 1988; 19(6):807-13.
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Treistman SN, Levitan IB. Alteration of electrical activity in molluscan neurones by cyclic nucleotides and peptide factors. Nature. 1976 May 06; 261(5555):62-4.