"Vinculin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequence of human vinculin has been determined. The protein consists of 1066 amino acid residues and its gene has been assigned to chromosome 10.
| Descriptor ID |
D016596
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| MeSH Number(s) |
D12.776.220.990
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vinculin".
Below are MeSH descriptors whose meaning is more specific than "Vinculin".
This graph shows the total number of publications written about "Vinculin" by people in this website by year, and whether "Vinculin" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Vinculin" by people in Profiles.
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Krokhotin A, Sarker M, Sevilla EA, Costantini LM, Griffith JD, Campbell SL, Dokholyan NV. Distinct Binding Modes of Vinculin Isoforms Underlie Their Functional Differences. Structure. 2019 10 01; 27(10):1527-1536.e3.
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Sarker M, Lee HT, Mei L, Krokhotin A, de Los Reyes SE, Yen L, Costantini LM, Griffith J, Dokholyan NV, Alushin GM, Campbell SL. Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies. J Mol Biol. 2019 04 05; 431(8):1604-1618.
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Kumar A, Nune KC, Misra RD. Electric field-mediated growth of osteoblasts - the significant impact of dynamic flow of medium. Biomater Sci. 2016 Jan; 4(1):136-44.
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Thievessen I, Fakhri N, Steinwachs J, Kraus V, McIsaac RS, Gao L, Chen BC, Baird MA, Davidson MW, Betzig E, Oldenbourg R, Waterman CM, Fabry B. Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen. FASEB J. 2015 Nov; 29(11):4555-67.
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Betzig E, Patterson GH, Sougrat R, Lindwasser OW, Olenych S, Bonifacino JS, Davidson MW, Lippincott-Schwartz J, Hess HF. Imaging intracellular fluorescent proteins at nanometer resolution. Science. 2006 Sep 15; 313(5793):1642-5.
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Lele TP, Pendse J, Kumar S, Salanga M, Karavitis J, Ingber DE. Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. J Cell Physiol. 2006 Apr; 207(1):187-94.
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Galloway PG, Perry G, Gambetti P. Hirano body filaments contain actin and actin-associated proteins. J Neuropathol Exp Neurol. 1987 Mar; 46(2):185-99.