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Lindsey Costantini

TitleAssistant Professor
Faculty RankAssistant Professor
InstitutionNorth Carolina Central University
DepartmentJulius L. Chambers Bimedical/Biotechnology Research Institute (BBRI)
Address700 George Street
Durham NC 27707
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    Collapse Research 
    Collapse research activities and funding
    SC2GM136527     (COSTANTINI, LINDSEY M)Apr 15, 2020 - Feb 29, 2024
    NIH
    Identifying novel activities of KSHV/HHV8 DNA replication proteins
    Role: Principal Investigator
    R16GM153198     (COSTANTINI, LINDSEY M)Apr 1, 2024 - Feb 29, 2028
    NIH
    Single Molecule analysis of KSHV/HHV8 DNA replication proteins
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Calhoun JC, Damania B, Griffith JD, Costantini LM. Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein. J Virol. 2023 10 31; 97(10):e0063723. PMID: 37750723.
      Citations:    Fields:    Translation:HumansCells
    2. Calhoun JC, Damania B, Griffith JD, Costantini LM. Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA protein. bioRxiv. 2023 May 01. PMID: 37205529.
      Citations:    
    3. McNamara RP, Zhou Y, Eason AB, Landis JT, Chambers MG, Willcox S, Peterson TA, Schouest B, Maness NJ, MacLean AG, Costantini LM, Griffith JD, Dittmer DP. Imaging of surface microdomains on individual extracellular vesicles in 3-D. J Extracell Vesicles. 2022 03; 11(3):e12191. PMID: 35234354.
      Citations: 16     Fields:    Translation:Cells
    4. McNamara RP, Eason AB, Zhou Y, Bigi R, Griffith JD, Costantini LM, Rudek MA, Anders NM, Damania BA, Dittmer DP. Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angiogenesis Activity. ACS Bio Med Chem Au. 2022 Apr 20; 2(2):140-149. PMID: 35480227.
      Citations:    
    5. Yeyeodu ST, Martin ME, Reaves DK, Enders JR, Costantini LM, Fleming JM. Experimental data demonstrating the effects of silver nanoparticles on basement membrane gene and protein expression in cultured colon, mammary and bronchial epithelia. Data Brief. 2019 Oct; 26:104464. PMID: 31667234.
      Citations:    
    6. Krokhotin A, Sarker M, Sevilla EA, Costantini LM, Griffith JD, Campbell SL, Dokholyan NV. Distinct Binding Modes of Vinculin Isoforms Underlie Their Functional Differences. Structure. 2019 10 01; 27(10):1527-1536.e3. PMID: 31422909.
      Citations: 2     Fields:    Translation:AnimalsCells
    7. Martin ME, Reaves DK, Jeffcoat B, Enders JR, Costantini LM, Yeyeodu ST, Botta D, Kavanagh TJ, Fleming JM. Silver nanoparticles alter epithelial basement membrane integrity, cell adhesion molecule expression, and TGF-?1 secretion. Nanomedicine. 2019 10; 21:102070. PMID: 31351238.
      Citations: 6     Fields:    Translation:HumansCells
    8. Sarker M, Lee HT, Mei L, Krokhotin A, de Los Reyes SE, Yen L, Costantini LM, Griffith J, Dokholyan NV, Alushin GM, Campbell SL. Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies. J Mol Biol. 2019 04 05; 431(8):1604-1618. PMID: 30844403.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    9. McNamara RP, Chugh PE, Bailey A, Costantini LM, Ma Z, Bigi R, Cheves A, Eason AB, Landis JT, Host KM, Xiong J, Griffith JD, Damania B, Dittmer DP. Extracellular vesicles from Kaposi Sarcoma-associated herpesvirus lymphoma induce long-term endothelial cell reprogramming. PLoS Pathog. 2019 02; 15(2):e1007536. PMID: 30716130.
      Citations: 32     Fields:    Translation:HumansCells
    10. McNamara RP, Caro-Vegas CP, Costantini LM, Landis JT, Griffith JD, Damania BA, Dittmer DP. Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles. J Extracell Vesicles. 2018; 7(1):1541396. PMID: 30533204.
      Citations: 38     Fields:    
    11. McNamara RP, Costantini LM, Myers TA, Schouest B, Maness NJ, Griffith JD, Damania BA, MacLean AG, Dittmer DP. Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses. mBio. 2018 02 06; 9(1). PMID: 29437924.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    12. Host KM, Jacobs SR, West JA, Zhang Z, Costantini LM, Stopford CM, Dittmer DP, Damania B. Kaposi's Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes. mBio. 2017 10 10; 8(5). PMID: 29018115.
      Citations: 30     Fields:    Translation:HumansCells
    13. Costantini LM, Snapp EL. Going Viral with Fluorescent Proteins. J Virol. 2015 Oct; 89(19):9706-8. PMID: 26202231.
      Citations: 8     Fields:    
    14. Costantini LM, Baloban M, Markwardt ML, Rizzo MA, Guo F, Verkhusha VV, Snapp EL. A palette of fluorescent proteins optimized for diverse cellular environments. Nat Commun. 2015 07 09; 6:7670. PMID: 26158227.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    15. Costantini LM, Irvin SC, Kennedy SC, Guo F, Goldstein H, Herold BC, Snapp EL. Engineering and exploitation of a fluorescent HIV-1 gp120 for live cell CD4 binding assays. Virology. 2015 Feb; 476:240-248. PMID: 25555152.
      Citations: 3     Fields:    Translation:HumansCells
    16. Costantini L, Snapp E. Probing endoplasmic reticulum dynamics using fluorescence imaging and photobleaching techniques. Curr Protoc Cell Biol. 2013 Sep 24; 60:21.7.1-21.7.29. PMID: 24510787.
      Citations: 8     Fields:    Translation:AnimalsCells
    17. Costantini LM, Snapp EL. Fluorescent proteins in cellular organelles: serious pitfalls and some solutions. DNA Cell Biol. 2013 Nov; 32(11):622-7. PMID: 23971632.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    18. Costantini LM, Subach OM, Jaureguiberry-bravo M, Verkhusha VV, Snapp EL. Cysteineless non-glycosylated monomeric blue fluorescent protein, secBFP2, for studies in the eukaryotic secretory pathway. Biochem Biophys Res Commun. 2013 Jan 18; 430(3):1114-9. PMID: 23257162.
      Citations: 11     Fields:    Translation:HumansCells
    19. Costantini LM, Fossati M, Francolini M, Snapp EL. Assessing the tendency of fluorescent proteins to oligomerize under physiologic conditions. Traffic. 2012 May; 13(5):643-9. PMID: 22289035.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    20. Howarth DL, Vacaru AM, Tsedensodnom O, Mormone E, Nieto N, Costantini LM, Snapp EL, Sadler KC. Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes. Alcohol Clin Exp Res. 2012 Jan; 36(1):14-23. PMID: 21790674.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    21. Aronson DE, Costantini LM, Snapp EL. Superfolder GFP is fluorescent in oxidizing environments when targeted via the Sec translocon. Traffic. 2011 May; 12(5):543-8. PMID: 21255213.
      Citations: 77     Fields:    Translation:HumansCells
    22. Costantini LM, Gilberti RM, Knecht DA. The phagocytosis and toxicity of amorphous silica. PLoS One. 2011 Feb 02; 6(2):e14647. PMID: 21311600.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
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