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Mice, SCID

"Mice, SCID" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.


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This graph shows the total number of publications written about "Mice, SCID" by people in this website by year, and whether "Mice, SCID" was a major or minor topic of these publications.
Bar chart showing 124 publications over 24 distinct years, with a maximum of 10 publications in 2010 and 2011
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