"Cytochalasin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
| Descriptor ID |
D015638
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| MeSH Number(s) |
D03.633.100.473.231.450 D23.946.587.370.450
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytochalasin D".
Below are MeSH descriptors whose meaning is more specific than "Cytochalasin D".
This graph shows the total number of publications written about "Cytochalasin D" by people in this website by year, and whether "Cytochalasin D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochalasin D" by people in Profiles.
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Fang Z, Takizawa N, Wilson KA, Smith TC, Delprato A, Davidson MW, Lambright DG, Luna EJ. The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility. Traffic. 2010 Jun; 11(6):782-99.
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Lele TP, Pendse J, Kumar S, Salanga M, Karavitis J, Ingber DE. Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. J Cell Physiol. 2006 Apr; 207(1):187-94.
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DeMaio L, Tarbell JM, Scaduto RC, Gardner TW, Antonetti DA. A transmural pressure gradient induces mechanical and biological adaptive responses in endothelial cells. Am J Physiol Heart Circ Physiol. 2004 Feb; 286(2):H731-41.
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Hill EM, Raji A, Valenzuela MS, Garcia F, Hoover R. Adhesion to and invasion of cultured human cells by Bartonella bacilliformis. Infect Immun. 1992 Oct; 60(10):4051-8.
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Jaynes JM, Julian GR, Jeffers GW, White KL, Enright FM. In vitro cytocidal effect of lytic peptides on several transformed mammalian cell lines. Pept Res. 1989 Mar-Apr; 2(2):157-60.