Chloramphenicol O-Acetyltransferase
"Chloramphenicol O-Acetyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.
| Descriptor ID |
D015500
|
| MeSH Number(s) |
D08.811.913.050.134.170
|
| Concept/Terms |
Chloramphenicol O-Acetyltransferase- Chloramphenicol O-Acetyltransferase
- Chloramphenicol O Acetyltransferase
- O-Acetyltransferase, Chloramphenicol
- Chloramphenicol Transacetylase
- Transacetylase, Chloramphenicol
- CAT Enzyme
- Enzyme, CAT
- Chloramphenicol Acetyltransferase
- Acetyltransferase, Chloramphenicol
|
Below are MeSH descriptors whose meaning is more general than "Chloramphenicol O-Acetyltransferase".
Below are MeSH descriptors whose meaning is more specific than "Chloramphenicol O-Acetyltransferase".
This graph shows the total number of publications written about "Chloramphenicol O-Acetyltransferase" by people in this website by year, and whether "Chloramphenicol O-Acetyltransferase" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chloramphenicol O-Acetyltransferase" by people in Profiles.
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Mukhopadhyay S, Sekhar KR, Hale AB, Channon KM, Farrugia G, Freeman ML, Gangula PR. Loss of NRF2 impairs gastric nitrergic stimulation and function. Free Radic Biol Med. 2011 Aug 01; 51(3):619-25.
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Yang K, Su WW. Facile synthesis of metal-chelating magnetic nanoparticles by exploiting organophosphorus coupling. Anal Biochem. 2011 Jan 01; 408(1):175-7.
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Swamy N, Chen TC, Peleg S, Dhawan P, Christakos S, Stewart LV, Weigel NL, Mehta RG, Holick MF, Ray R. Inhibition of proliferation and induction of apoptosis by 25-hydroxyvitamin D3-3beta-(2)-Bromoacetate, a nontoxic and vitamin D receptor-alkylating analog of 25-hydroxyvitamin D3 in prostate cancer cells. Clin Cancer Res. 2004 Dec 01; 10(23):8018-27.
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Walpita P. An internal element of the measles virus antigenome promoter modulates replication efficiency. Virus Res. 2004 Mar 15; 100(2):199-211.
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Tchounwou PB, Yedjou CG, Foxx DN, Ishaque AB, Shen E. Lead-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells. Mol Cell Biochem. 2004 Jan; 255(1-2):161-70.
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Hatada S, Grant DJ, Maeda N. An intronic endogenous retrovirus-like sequence attenuates human haptoglobin-related gene expression in an orientation-dependent manner. Gene. 2003 Nov 13; 319:55-63.
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Kurtz DM, Tian L, Gower BA, Nagy TR, Pinkert CA, Wood PA. Transgenic studies of fatty acid oxidation gene expression in nonobese diabetic mice. J Lipid Res. 2000 Dec; 41(12):2063-70.
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Bergeron LJ, Morou-Bermudez E, Burne RA. Characterization of the fructosyltransferase gene of Actinomyces naeslundii WVU45. J Bacteriol. 2000 Jul; 182(13):3649-54.
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Zhang LP, Stroud J, Eddy CA, Walter CA, McCarrey JR. Multiple elements influence transcriptional regulation from the human testis-specific PGK2 promoter in transgenic mice. Biol Reprod. 1999 Jun; 60(6):1329-37.
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Chaudhary J, Skinner MK. Basic helix-loop-helix proteins can act at the E-box within the serum response element of the c-fos promoter to influence hormone-induced promoter activation in Sertoli cells. Mol Endocrinol. 1999 May; 13(5):774-86.