"Tachykinins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of biologically active peptides sharing a common conserved C-terminal sequence, -Phe-X-Gly-Leu-Met-NH2, where X is either an aromatic or a branched aliphatic amino acid. Members of this family have been found in mammals, amphibians, and mollusks. Tachykinins have diverse pharmacological actions in the central nervous system and the cardiovascular, genitourinary, respiratory, and gastrointestinal systems, as well as in glandular tissues. This diversity of activity is due to the existence of three or more subtypes of tachykinin receptors.
Descriptor ID |
D015320
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MeSH Number(s) |
D12.644.276.812.900 D12.644.400.800 D12.644.456.800 D12.776.467.812.900 D12.776.631.650.800 D23.469.050.375.850 D23.529.812.900
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tachykinins".
Below are MeSH descriptors whose meaning is more specific than "Tachykinins".
This graph shows the total number of publications written about "Tachykinins" by people in this website by year, and whether "Tachykinins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 1 | 2 |
1997 | 1 | 0 | 1 |
2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tachykinins" by people in Profiles.
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Pete G, Mack SO, Haxhiu MA, Walbaum S, Gauda EB. CO(2)-induced c-Fos expression in brainstem preprotachykinin mRNA containing neurons. Respir Physiol Neurobiol. 2002 Jun; 130(3):265-74.
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Kraft M, Noailles P, Angulo JA. Substance P modulates cocaine-evoked dopamine overflow in the striatum of the rat brain. Ann N Y Acad Sci. 2001 Jun; 937:121-31.
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Zhang Y, Landas K, Mueller H, Angulo JA. Progressive augmentation of striatal and accumbal preprotachykinin mRNA levels by chronic treatment with methamphetamine and effect of concurrent administration of the N-methyl-D-aspartate receptor antagonist MK-801. Neuropharmacology. 1997 Mar; 36(3):325-34.
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Villegas M, Angulo JA. Attenuation of neostriatal preproenkephalin and preprotachykinin mRNA abundance by chronic treatment with the kainate/quisqualate receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione in the rat brain. Neurosci Lett. 1995 May 19; 191(1-2):51-4.
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Angulo JA, Williams A, Ledoux M, Watanabe Y, McEwen BS. Elevation of striatal and accumbal preproenkephalin, preprotachykinin and preprodynorphin mRNA abundance subsequent to N-methyl-D-aspartate receptor blockade with MK-801. Brain Res Mol Brain Res. 1995 Mar; 29(1):15-22.