"Neurotensin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biologically active tridecapeptide isolated from the hypothalamus. It has been shown to induce hypotension in the rat, to stimulate contraction of guinea pig ileum and rat uterus, and to cause relaxation of rat duodenum. There is also evidence that it acts as both a peripheral and a central nervous system neurotransmitter.
| Descriptor ID |
D009496
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| MeSH Number(s) |
D12.644.400.550 D12.776.631.650.550
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurotensin".
Below are MeSH descriptors whose meaning is more specific than "Neurotensin".
This graph shows the total number of publications written about "Neurotensin" by people in this website by year, and whether "Neurotensin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurotensin" by people in Profiles.
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Liu Q, Hazan A, Grinman E, Angulo JA. Pharmacological activation of the neurotensin receptor 1 abrogates the methamphetamine-induced striatal apoptosis in the mouse brain. Brain Res. 2017 03 15; 1659:148-155.
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Li J, O'Connor KL, Hellmich MR, Greeley GH, Townsend CM, Evers BM. The role of protein kinase D in neurotensin secretion mediated by protein kinase C-alpha/-delta and Rho/Rho kinase. J Biol Chem. 2004 Jul 02; 279(27):28466-74.
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Alexander LD, Sander LD. VIP antagonist demonstrates differences in VIP- and PHI-mediated stimulation and inhibition of ACTH and corticosterone secretion in rats. Regul Pept. 1995 Nov 10; 59(3):321-33.
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Angulo JA, McEwen BS. Molecular aspects of neuropeptide regulation and function in the corpus striatum and nucleus accumbens. Brain Res Brain Res Rev. 1994 Jan; 19(1):1-28.