Thyrotropin-Releasing Hormone

"Thyrotropin-Releasing Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A tripeptide that stimulates the release of THYROTROPIN and PROLACTIN. It is synthesized by the neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, TRH (was called TRF) stimulates the release of TSH and PRL from the ANTERIOR PITUITARY GLAND.

Descriptor ID	D013973
MeSH Number(s)	D06.472.699.327.740.880 D12.644.400.400.740.880 D12.644.456.837 D12.644.548.365.740.880 D12.776.631.650.405.740.880 D12.776.631.650.810
Concept/Terms	Thyrotropin-Releasing Hormone Thyrotropin-Releasing Hormone Thyrotropin Releasing Hormone Thyrotropin-Releasing Factor Thyrotropin Releasing Factor Protirelin Antepan Antepan Protirelin Tartrate (1:1) Protirelin Tartrate (1:1) Proterelin Tartrate Thyrotropin-Releasing Hormone Tartrate Thyrotropin Releasing Hormone Tartrate Relefact TRH Relefact TRH TRH, Relefact Thypinone Thypinone Thyroliberin Thyroliberin Thyroliberin TRH Merck TRH Prem TRH Prem Prem, TRH Proterelin Tartrate Hydrate Proterelin Tartrate Hydrate Hydrate, Proterelin Tartrate Tartrate Hydrate, Proterelin Abbott-38579 Abbott-38579 Abbott 38579 Abbott38579 Stimu-TSH Stimu-TSH Stimu TSH StimuTSH TRH Ferring

Below are MeSH descriptors whose meaning is more general than "Thyrotropin-Releasing Hormone".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Hypothalamic Hormones [D06.472.699.327]
Pituitary Hormone-Releasing Hormones [D06.472.699.327.740]
Thyrotropin-Releasing Hormone [D06.472.699.327.740.880]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Hypothalamic Hormones [D12.644.400.400]
Pituitary Hormone-Releasing Hormones [D12.644.400.400.740]
Thyrotropin-Releasing Hormone [D12.644.400.400.740.880]
Oligopeptides [D12.644.456]
Thyrotropin-Releasing Hormone [D12.644.456.837]
Peptide Hormones [D12.644.548]
Hypothalamic Hormones [D12.644.548.365]
Pituitary Hormone-Releasing Hormones [D12.644.548.365.740]
Thyrotropin-Releasing Hormone [D12.644.548.365.740.880]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Hypothalamic Hormones [D12.776.631.650.405]
Pituitary Hormone-Releasing Hormones [D12.776.631.650.405.740]
Thyrotropin-Releasing Hormone [D12.776.631.650.405.740.880]
Thyrotropin-Releasing Hormone [D12.776.631.650.810]

Below are MeSH descriptors whose meaning is related to "Thyrotropin-Releasing Hormone".

Below are MeSH descriptors whose meaning is more specific than "Thyrotropin-Releasing Hormone".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Thyrotropin-Releasing Hormone" by people in this website by year, and whether "Thyrotropin-Releasing Hormone" was a major or minor topic of these publications.

Bar chart showing 7 publications over 4 distinct years, with a maximum of 3 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	1	2
2006	2	1	3
2008	0	1	1
2010	1	0	1

Below are the most recent publications written about "Thyrotropin-Releasing Hormone" by people in Profiles.

P?rez-Monter C, Mart?nez-Armenta M, Miquelajauregui A, Furlan-Magaril M, Varela-Echavarr?a A, Recillas-Targa F, May V, Charli JL, P?rez-Mart?nez L. The Kr?ppel-like factor 4 controls biosynthesis of thyrotropin-releasing hormone during hypothalamus development. Mol Cell Endocrinol. 2011 Feb 20; 333(2):127-33.

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Espinosa VP, Liu Y, Ferrini M, Anghel A, Nie Y, Tripathi PV, Porche R, Jansen E, Stuart RC, Nillni EA, Lutfy K, Friedman TC. Differential regulation of prohormone convertase 1/3, prohormone convertase 2 and phosphorylated cyclic-AMP-response element binding protein by short-term and long-term morphine treatment: implications for understanding the "switch" to opiate addiction. Neuroscience. 2008 Oct 15; 156(3):788-99.

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Hsieh YL, Chowdhury I, Chien JT, Chatterjee A, Yu JY. Molecular cloning and sequence analysis of the cDNA encoding thyroid-stimulating hormone beta-subunit of common duck and mule duck pituitaries: in vitro regulation of steady-state TSHbeta mRNA level. Comp Biochem Physiol B Biochem Mol Biol. 2007 Mar; 146(3):307-17.

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Espinosa VP, Ferrini M, Shen X, Lutfy K, Nillni EA, Friedman TC. Cellular colocalization and coregulation between hypothalamic pro-TRH and prohormone convertases in hypothyroidism. Am J Physiol Endocrinol Metab. 2007 Jan; 292(1):E175-86.

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Perello M, Friedman T, Paez-Espinosa V, Shen X, Stuart RC, Nillni EA. Thyroid hormones selectively regulate the posttranslational processing of prothyrotropin-releasing hormone in the paraventricular nucleus of the hypothalamus. Endocrinology. 2006 Jun; 147(6):2705-16.

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Chowdhury I, Chien JT, Chatterjee A, Yu JY. Effects of leptin and neuropeptide-Y on transcript levels of thyrotropin beta and common alpha subunits of rat pituitary cells in vitro. Life Sci. 2004 Oct 29; 75(24):2897-909.

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Sanchez VC, Goldstein J, Stuart RC, Hovanesian V, Huo L, Munzberg H, Friedman TC, Bjorbaek C, Nillni EA. Regulation of hypothalamic prohormone convertases 1 and 2 and effects on processing of prothyrotropin-releasing hormone. J Clin Invest. 2004 Aug; 114(3):357-69.

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Khorram O, De Palatis LR, Krulich L, McCann SM. The development of prolactin, growth hormone, alpha-melanocyte-stimulating hormone and monoaminergic systems in the rat. Monogr Neural Sci. 1986; 12:1-6.

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Khorram O, Depalatis LR, McCann SM. Hypothalamic control of prolactin secretion during the perinatal period in the rat. Endocrinology. 1984 Nov; 115(5):1698-704.

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Sugerman AA, Swartzburg M, Mueller PS, Rochford J. Oral protirelin (T.R.H.) in depression. Curr Ther Res Clin Exp. 1976 Jan; 19(1):94-8.

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