Wiskott-Aldrich Syndrome

"Wiskott-Aldrich Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A rare, X-linked immunodeficiency syndrome characterized by ECZEMA; LYMPHOPENIA; and, recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.

Descriptor ID	D014923
MeSH Number(s)	C15.378.100.100.970 C15.378.463.960 C15.378.553.546.605.900 C16.320.099.970 C16.320.322.937 C20.673.627.900
Concept/Terms	Wiskott-Aldrich Syndrome Wiskott-Aldrich Syndrome Syndrome, Wiskott-Aldrich Wiskott Aldrich Syndrome Wiskott Syndrome Imd2 Immunodeficiency 2 Aldrich Syndrome Syndrome, Aldrich Eczema-Thrombocytopenia-Immunodeficiency Syndrome Eczema Thrombocytopenia Immunodeficiency Syndrome Eczema-Thrombocytopenia-Immunodeficiency Syndromes Syndrome, Eczema-Thrombocytopenia-Immunodeficiency Syndromes, Eczema-Thrombocytopenia-Immunodeficiency

Below are MeSH descriptors whose meaning is more general than "Wiskott-Aldrich Syndrome".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Blood Coagulation Disorders [C15.378.100]
Blood Coagulation Disorders, Inherited [C15.378.100.100]
Wiskott-Aldrich Syndrome [C15.378.100.100.970]
Hemorrhagic Disorders [C15.378.463]
Wiskott-Aldrich Syndrome [C15.378.463.960]
Leukocyte Disorders [C15.378.553]
Leukopenia [C15.378.553.546]
Lymphopenia [C15.378.553.546.605]
Wiskott-Aldrich Syndrome [C15.378.553.546.605.900]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Blood Coagulation Disorders, Inherited [C16.320.099]
Wiskott-Aldrich Syndrome [C16.320.099.970]
Genetic Diseases, X-Linked [C16.320.322]
Wiskott-Aldrich Syndrome [C16.320.322.937]
Immune System Diseases [C20]
Immunologic Deficiency Syndromes [C20.673]
Lymphopenia [C20.673.627]
Wiskott-Aldrich Syndrome [C20.673.627.900]

Below are MeSH descriptors whose meaning is related to "Wiskott-Aldrich Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Wiskott-Aldrich Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Wiskott-Aldrich Syndrome" by people in this website by year, and whether "Wiskott-Aldrich Syndrome" was a major or minor topic of these publications.

Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 2003 and 2007 and 2020 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Total
2003	1	1
2007	1	1
2020	1	1
2023	1	1

Below are the most recent publications written about "Wiskott-Aldrich Syndrome" by people in Profiles.

Alexander JL, D?vila Salda?a BJ, Brazauskas R, Dammalapati SG, Griffith LM, Shah AJ, Shimano KA, Ochs HD, Bleesing JJ, Ebens CL, Kapadia M, Bauchat A, Kapoor N, Oved JH, Eissa H, Lust H, Keller MD, Haines H, Chandrakasan S, Talano JA, Rayes A, Madden L, Shereck E, Miller HK, Satter LF, Martinez C, Rozmus J, Bednarski JJ, Yu LC, Chellapandian D, Aquino VM, Knutsen A, Chong H, Chopek A, Gillio AP, Joshi A, Rangarajan H, Moore TB, Andolina JR, DeSantes KB, Vander Lugt M, Prockop SE, Shyr DC, Sullivan KE, Parikh S, Weinacht KG, Torgerson TR, Marsh R, Dvorak CC, Chan AY, Haddad E, Heimall JR, Pulsipher MA, Leiding JW, Kohn DB, Puck JM, Notarangelo LD, Rawlings DJ, Cowan MJ, Petrovic A, Pai SY, Burroughs LM. Hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report. Blood Adv. 2026 Mar 10; 10(5):1783-1798.

View in: PubMed
Chandrakasan S, Westbrook A, Griffith LM, Hagin D, Iyengar S, Mangurian C, Scalchunes C, Sullivan KE, Zablocki A, Bakshi N, Sinha C, Burroughs LM, Chan AY, Dvorak CC, Haddad E, Heimall J, Kohn DB, Leiding JW, Notarangelo LD, Pai SY, Puck JM, Pulsipher MA, Marsh RA, Torgerson T, Cowan MJ, Ochs HD, Parikh S. Clinical spectrum of Wiskott-Aldrich syndrome carriers: Self-reported survey of 193 carriers. Clin Immunol. 2026 Feb; 283:110658.

View in: PubMed
M?ndez Barrera JA, Rocha Guzm?n S, Hierro Cascajares E, Garabedian EK, Fuleihan RL, Sullivan KE, Lugo Reyes SO. Who's your data? Primary immune deficiency differential diagnosis prediction via machine learning and data mining of the USIDNET registry. Clin Immunol. 2023 10; 255:109759.

View in: PubMed
Burroughs LM, Petrovic A, Brazauskas R, Liu X, Griffith LM, Ochs HD, Bleesing JJ, Edwards S, Dvorak CC, Chaudhury S, Prockop SE, Quinones R, Goldman FD, Quigg TC, Chandrakasan S, Smith AR, Parikh S, D?vila Salda?a BJ, Thakar MS, Phelan R, Shenoy S, Forbes LR, Martinez C, Chellapandian D, Shereck E, Miller HK, Kapoor N, Barnum JL, Chong H, Shyr DC, Chen K, Abu-Arja R, Shah AJ, Weinacht KG, Moore TB, Joshi A, DeSantes KB, Gillio AP, Cuvelier GDE, Keller MD, Rozmus J, Torgerson T, Pulsipher MA, Haddad E, Sullivan KE, Logan BR, Kohn DB, Puck JM, Notarangelo LD, Pai SY, Rawlings DJ, Cowan MJ. Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report. Blood. 2020 06 04; 135(23):2094-2105.

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Adriani M, Aoki J, Horai R, Thornton AM, Konno A, Kirby M, Anderson SM, Siegel RM, Candotti F, Schwartzberg PL. Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome. Clin Immunol. 2007 Jul; 124(1):41-8.

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Kitamura Y, Tsuchiya D, Takata K, Shibagaki K, Taniguchi T, Smith MA, Perry G, Miki H, Takenawa T, Shimohama S. Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease. Neurosci Lett. 2003 Aug 07; 346(3):149-52.

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