Muscular Dystrophy, Duchenne

"Muscular Dystrophy, Duchenne" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)

Descriptor ID	D020388
MeSH Number(s)	C05.651.534.500.300 C10.668.491.175.500.300 C16.320.322.562 C16.320.577.300
Concept/Terms	Muscular Dystrophy, Duchenne Muscular Dystrophy, Duchenne Cardiomyopathy, Dilated, X-Linked Childhood Muscular Dystrophy, Pseudohypertrophic Childhood Pseudohypertrophic Muscular Dystrophy Duchenne Muscular Dystrophy Duchenne-Type Progressive Muscular Dystrophy Duchenne Type Progressive Muscular Dystrophy Muscular Dystrophy, Childhood, Pseudohypertrophic Muscular Dystrophy, Duchenne Type Muscular Dystrophy, Pseudohypertrophic Pseudohypertrophic Muscular Dystrophy Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type Muscular Dystrophy, Pseudohypertrophic, Childhood Progressive Muscular Dystrophy, Duchenne Type Pseudohypertrophic Childhood Muscular Dystrophy Pseudohypertrophic Muscular Dystrophy, Childhood Cardiomyopathy, Dilated, 3B Duchenne and Becker Muscular Dystrophy Duchenne and Becker Muscular Dystrophy Muscular Dystrophy, Duchenne and Becker Types Duchenne-Becker Muscular Dystrophy Duchenne Becker Muscular Dystrophy Muscular Dystrophy, Duchenne-Becker Becker Muscular Dystrophy Becker Muscular Dystrophy Muscular Dystrophy, Pseudohypertrophic Progressive, Becker Type Muscular Dystrophy, Becker Muscular Dystrophy, Becker Type Becker's Muscular Dystrophy Muscular Dystrophy, Becker's Muscular Dystrophy Pseudohypertrophic Progressive, Becker Type

Below are MeSH descriptors whose meaning is more general than "Muscular Dystrophy, Duchenne".

Diseases [C]
Musculoskeletal Diseases [C05]
Muscular Diseases [C05.651]
Muscular Disorders, Atrophic [C05.651.534]
Muscular Dystrophies [C05.651.534.500]
Muscular Dystrophy, Duchenne [C05.651.534.500.300]
Nervous System Diseases [C10]
Neuromuscular Diseases [C10.668]
Muscular Diseases [C10.668.491]
Muscular Disorders, Atrophic [C10.668.491.175]
Muscular Dystrophies [C10.668.491.175.500]
Muscular Dystrophy, Duchenne [C10.668.491.175.500.300]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Genetic Diseases, X-Linked [C16.320.322]
Muscular Dystrophy, Duchenne [C16.320.322.562]
Muscular Dystrophies [C16.320.577]
Muscular Dystrophy, Duchenne [C16.320.577.300]

Below are MeSH descriptors whose meaning is related to "Muscular Dystrophy, Duchenne".

Below are MeSH descriptors whose meaning is more specific than "Muscular Dystrophy, Duchenne".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Muscular Dystrophy, Duchenne" by people in this website by year, and whether "Muscular Dystrophy, Duchenne" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 1999 and 2001 and 2004 and 2013 and 2014 and 2016 and 2017 and 2019 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2001	1	0	1
2004	0	1	1
2013	0	1	1
2014	0	1	1
2016	1	0	1
2017	1	0	1
2019	1	0	1
2022	1	0	1

Below are the most recent publications written about "Muscular Dystrophy, Duchenne" by people in Profiles.

Sakai K, Motegi T, Chambers JK, Uchida K, Nishida H, Shimamura S, Tani H, Shimada T, Furuya M. Dystrophin-deficient muscular dystrophy in a Toy Poodle with a single base pair insertion in exon 45 of the Duchenne muscular dystrophy gene. J Vet Med Sci. 2022 Apr 13; 84(4):502-506.

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Hughes MC, Ramos SV, Turnbull PC, Rebalka IA, Cao A, Monaco CMF, Varah NE, Edgett BA, Huber JS, Tadi P, Delfinis LJ, Schlattner U, Simpson JA, Hawke TJ, Perry CGR. Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H2 O2 emission during impaired oxidative phosphorylation. J Cachexia Sarcopenia Muscle. 2019 06; 10(3):643-661.

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Doe J, Kaindl AM, Jijiwa M, de la Vega M, Hu H, Griffiths GS, Fontelonga TM, Barraza P, Cruz V, Van Ry P, Ramos JW, Burkin DJ, Matter ML. PTRH2 gene mutation causes progressive congenital skeletal muscle pathology. Hum Mol Genet. 2017 04 15; 26(8):1458-1464.

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Ramos E, Conde JG, Berrios RA, Pardo S, G?mez O, Mas Rodr?guez MF. Prevalence and Genetic Profile of Duchene and Becker Muscular Dystrophy in Puerto Rico. J Neuromuscul Dis. 2016 05 27; 3(2):261-266.

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Heier CR, Guerron AD, Korotcov A, Lin S, Gordish-Dressman H, Fricke S, Sze RW, Hoffman EP, Wang P, Nagaraju K. Non-invasive MRI and spectroscopy of mdx mice reveal temporal changes in dystrophic muscle imaging and in energy deficits. PLoS One. 2014; 9(11):e112477.

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Tsao J, Vernet DA, Gelfand R, Kovanecz I, Nolazco G, Bruhn KW, Gonzalez-Cadavid NF. Myostatin genetic inactivation inhibits myogenesis by muscle-derived stem cells in vitro but not when implanted in the mdx mouse muscle. Stem Cell Res Ther. 2013 Jan 07; 4(1):4.

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Zhou YW, Oak SA, Senogles SE, Jarrett HW. Laminin-alpha1 globular domains 3 and 4 induce heterotrimeric G protein binding to alpha-syntrophin's PDZ domain and alter intracellular Ca2+ in muscle. Am J Physiol Cell Physiol. 2005 Feb; 288(2):C377-88.

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Bola?os-Jim?nez F, Bordais A, Behra M, Str?hle U, Mornet D, Sahel J, Rend?n A. Molecular cloning and characterization of dystrophin and Dp71, two products of the Duchenne Muscular Dystrophy gene, in zebrafish. Gene. 2001 Aug 22; 274(1-2):217-26.

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Madhavan R, Jarrett HW. Phosphorylation of dystrophin and alpha-syntrophin by Ca(2+)-calmodulin dependent protein kinase II. Biochim Biophys Acta. 1999 Oct 12; 1434(2):260-74.

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