Saponins

"Saponins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A type of glycoside widely distributed in plants. Each consists of a sapogenin as the aglycone moiety, and a sugar. The sapogenin may be a steroid or a triterpene and the sugar may be glucose, galactose, a pentose, or a methylpentose.

Descriptor ID	D012503
MeSH Number(s)	D09.408.782
Concept/Terms	Saponins Saponins Saponin Saponin

Below are MeSH descriptors whose meaning is more general than "Saponins".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycosides [D09.408]
Saponins [D09.408.782]

Below are MeSH descriptors whose meaning is related to "Saponins".

Below are MeSH descriptors whose meaning is more specific than "Saponins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Saponins" by people in this website by year, and whether "Saponins" was a major or minor topic of these publications.

Bar chart showing 7 publications over 7 distinct years, with a maximum of 1 publications in 2001 and 2007 and 2008 and 2015 and 2018 and 2021 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	0	1
2007	1	0	1
2008	1	0	1
2015	0	1	1
2018	0	1	1
2021	1	0	1
2023	1	0	1

Below are the most recent publications written about "Saponins" by people in Profiles.

Jesus MM, Lage DP, Vale DL, Freitas CS, Pimenta BL, Moreira GJL, Ramos FF, Pereira IAG, Bandeira RS, Ludolf F, Tavares GSV, Galdino AS, Duarte MC, Menezes-Souza D, Ch?vez-Fumagalli MA, Teixeira AL, Gon?alves DU, Roatt BM, Christodoulides M, Martins VT, Coelho EAF. Immunization with recombinant LiHyp1 protein plus adjuvant is protective against tegumentary leishmaniasis. Parasitol Res. 2023 Dec; 122(12):2917-2931.

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Monz?n Daza G, Meneses Mac?as C, Forero AM, Rodr?guez J, Arag?n M, Jim?nez C, Ramos FA, Castellanos L. Identification of a-Amylase and a-Glucosidase Inhibitors and Ligularoside A, a New Triterpenoid Saponin from Passiflora ligularis Juss (Sweet Granadilla) Leaves, by a Nuclear Magnetic Resonance-Based Metabolomic Study. J Agric Food Chem. 2021 Mar 10; 69(9):2919-2931.

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Dias DS, Ribeiro PAF, Martins VT, Lage DP, Costa LE, Ch?vez-Fumagalli MA, Ramos FF, Santos TTO, Ludolf F, Oliveira JS, Mendes TAO, Silva ES, Galdino AS, Duarte MC, Roatt BM, Menezes-Souza D, Teixeira AL, Coelho EAF. Vaccination with a CD4+ and CD8+ T-cell epitopes-based recombinant chimeric protein derived from Leishmania infantum proteins confers protective immunity against visceral leishmaniasis. Transl Res. 2018 10; 200:18-34.

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Peng S, Wang JW, Karanam B, Wang C, Huh WK, Alvarez RD, Pai SI, Hung CF, Wu TC, Roden RB. Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer. PLoS One. 2015; 10(1):e116389.

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Karanam B, Gambhira R, Peng S, Jagu S, Kim DJ, Ketner GW, Stern PL, Adams RJ, Roden RB. Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity. Vaccine. 2009 Feb 11; 27(7):1040-9.

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Calabria LM, Piacente S, Kapusta I, Dharmawardhane SF, Segarra FM, Pessiki PJ, Mabry TJ. Triterpene saponins from Silphium radula. Phytochemistry. 2008 Feb; 69(4):961-72.

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Zhang XF, Cui Y, Huang JJ, Zhang YZ, Nie Z, Wang LF, Yan BZ, Tang YL, Liu Y. Immuno-stimulating properties of diosgenyl saponins isolated from Paris polyphylla. Bioorg Med Chem Lett. 2007 May 01; 17(9):2408-13.

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Harding WW, Jacobs H, Lewis PA, McLean S, Reynolds WF. Cycloartanes, protolimonoids, a pregnane and a new ergostane from Trichilia reticulata. Nat Prod Lett. 2001; 15(4):253-60.

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Wu JY, Gardner BH, Murphy CI, Seals JR, Kensil CR, Recchia J, Beltz GA, Newman GW, Newman MJ. Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine. J Immunol. 1992 Mar 01; 148(5):1519-25.

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