"Novobiocin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189)
| Descriptor ID |
D009675
|
| MeSH Number(s) |
D03.383.663.283.446.139.500 D03.633.100.150.446.139.500 D09.408.554
|
| Concept/Terms |
Novobiocin- Novobiocin
- Streptonivicin
- Crystallinic Acid
Novobiocin Sodium- Novobiocin Sodium
- Sodium, Novobiocin
- Novobiocin, Monosodium Salt
- Monosodium Salt Novobiocin
|
Below are MeSH descriptors whose meaning is more general than "Novobiocin".
Below are MeSH descriptors whose meaning is more specific than "Novobiocin".
This graph shows the total number of publications written about "Novobiocin" by people in this website by year, and whether "Novobiocin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Novobiocin" by people in Profiles.
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Cheenpracha S, Vidor NB, Yoshida WY, Davies J, Chang LC. Coumabiocins A-F, aminocoumarins from an organic extract of Streptomyces sp. L-4-4. J Nat Prod. 2010 May 28; 73(5):880-4.
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Villeponteau B, Lundell M, Martinson H. Torsional stress promotes the DNAase I sensitivity of active genes. Cell. 1984 Dec; 39(3 Pt 2):469-78.