"Retinal Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Descriptor ID |
D012162
|
| MeSH Number(s) |
C11.768.585
|
| Concept/Terms |
Retinal Degeneration- Retinal Degeneration
- Degeneration, Retinal
- Degenerations, Retinal
- Retinal Degenerations
|
Below are MeSH descriptors whose meaning is more general than "Retinal Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Retinal Degeneration".
This graph shows the total number of publications written about "Retinal Degeneration" by people in this website by year, and whether "Retinal Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2007 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Retinal Degeneration" by people in Profiles.
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Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH. Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10).
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Goyal V, DeVera C, Baba K, Sellers J, Chrenek MA, Iuvone PM, Tosini G. Photoreceptor Degeneration in Homozygous Male Per2luc Mice During Aging. J Biol Rhythms. 2021 04; 36(2):137-145.
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Baba K, Ribelayga CP, Michael Iuvone P, Tosini G. The Retinal Circadian Clock and Photoreceptor Viability. Adv Exp Med Biol. 2018; 1074:345-350.
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Iuvone PM, Boatright JH, Tosini G, Ye K. N-acetylserotonin: circadian activation of the BDNF receptor and neuroprotection in the retina and brain. Adv Exp Med Biol. 2014; 801:765-71.
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O'Quin KE, Yoshizawa M, Doshi P, Jeffery WR. Quantitative genetic analysis of retinal degeneration in the blind cavefish Astyanax mexicanus. PLoS One. 2013; 8(2):e57281.
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Tosini G, Baba K, Hwang CK, Iuvone PM. Melatonin: an underappreciated player in retinal physiology and pathophysiology. Exp Eye Res. 2012 Oct; 103:82-9.
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Baba K, Pozdeyev N, Mazzoni F, Contreras-Alcantara S, Liu C, Kasamatsu M, Martinez-Merlos T, Strettoi E, Iuvone PM, Tosini G. Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):15043-8.
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Tosini G, Kasamatsu M, Sakamoto K. Clock gene expression in the rat retina: effects of lighting conditions and photoreceptor degeneration. Brain Res. 2007 Jul 23; 1159:134-40.
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Tosini G, Aguzzi J, Bullock NM, Liu C, Kasamatsu M. Effect of photoreceptor degeneration on circadian photoreception and free-running period in the Royal College of Surgeons rat. Brain Res. 2007 May 07; 1148:76-82.
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Sakamoto K, Liu C, Tosini G. Classical photoreceptors regulate melanopsin mRNA levels in the rat retina. J Neurosci. 2004 Oct 27; 24(43):9693-7.