Putrescine

"Putrescine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine.

Descriptor ID	D011700
MeSH Number(s)	D02.092.211.415.701 D02.092.782.258.784
Concept/Terms	Putrescine Putrescine 1,4-Diaminobutane 1,4 Diaminobutane Tetramethylenediamine 1,4-Butanediamine 1,4 Butanediamine

Below are MeSH descriptors whose meaning is more general than "Putrescine".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amines [D02.092]
Biogenic Amines [D02.092.211]
Biogenic Polyamines [D02.092.211.415]
Putrescine [D02.092.211.415.701]
Polyamines [D02.092.782]
Diamines [D02.092.782.258]
Putrescine [D02.092.782.258.784]

Below are MeSH descriptors whose meaning is related to "Putrescine".

Below are MeSH descriptors whose meaning is more specific than "Putrescine".

Putrescine
Spermidine

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Putrescine" by people in this website by year, and whether "Putrescine" was a major or minor topic of these publications.

Bar chart showing 9 publications over 7 distinct years, with a maximum of 2 publications in 2011 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2002	0	1	1
2006	1	0	1
2011	1	1	2
2013	0	1	1
2017	0	1	1
2022	1	1	2

Below are the most recent publications written about "Putrescine" by people in Profiles.

Sugiyama Y, Nakamura A, Ohta H, Fujita T, Kontani Y, Shimokawa H, Hirano R, Ami Y, Sakanaka M, Matsumoto M, Kurihara S. PstSCAB and SapBCDF are putrescine exporters in Proteus mirabilis. Microbiol Spectr. 2026 Jan 06; 14(1):e0430623.

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Kov?cs Z, Skatchkov SN, Szab? Z, Qahtan S, M?ndez-Gonz?lez MP, Malpica-Nieves CJ, Eaton MJ, Kardos J, H?ja L. Putrescine Intensifies Glu/GABA Exchange Mechanism and Promotes Early Termination of Seizures. Int J Mol Sci. 2022 Jul 25; 23(15).

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Rieck J, Skatchkov SN, Derst C, Eaton MJ, Veh RW. Unique Chemistry, Intake, and Metabolism of Polyamines in the Central Nervous System (CNS) and Its Body. Biomolecules. 2022 03 25; 12(4).

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Cai YS, Sarotti AM, G?ndisch D, Kondratyuk TP, Pezzuto JM, Turkson J, Cao S. Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities. Bioorg Med Chem Lett. 2017 10 15; 27(20):4630-4634.

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Sala-Rabanal M, Li DC, Dake GR, Kurata HT, Inyushin M, Skatchkov SN, Nichols CG. Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3. Mol Pharm. 2013 Apr 01; 10(4):1450-8.

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Duan B, Wang YZ, Yang T, Chu XP, Yu Y, Huang Y, Cao H, Hansen J, Simon RP, Zhu MX, Xiong ZG, Xu TL. Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis. J Neurosci. 2011 Feb 09; 31(6):2101-12.

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Puntambekar SS, Davis DS, Hawel L, Crane J, Byus CV, Carson MJ. LPS-induced CCL2 expression and macrophage influx into the murine central nervous system is polyamine-dependent. Brain Behav Immun. 2011 May; 25(4):629-39.

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Kandimalla KK, Curran GL, Holasek SS, Gilles EJ, Wengenack TM, Ramirez-Alvarado M, Poduslo JF. Physiological and biophysical factors that influence Alzheimer's disease amyloid plaque targeting of native and putrescine modified human amyloid beta40. J Pharmacol Exp Ther. 2006 Jul; 318(1):17-25.

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Abukhalaf IK, von Deutsch DA, Wineski LE, Silvestrov NA, Abera SA, Sahlu SW, Potter DE. Effect of hindlimb suspension and clenbuterol treatment on polyamine levels in skeletal muscle. Pharmacology. 2002 Jul; 65(3):145-54.

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Guevara-Olvera L, Hung CY, Yu JJ, Cole GT. Sequence, expression and functional analysis of the Coccidioides immitis ODC (ornithine decarboxylase) gene. Gene. 2000 Jan 25; 242(1-2):437-48.

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