"Spermidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
| Descriptor ID |
D013095
|
| MeSH Number(s) |
D02.092.211.415.701.801 D02.092.782.677
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spermidine".
Below are MeSH descriptors whose meaning is more specific than "Spermidine".
This graph shows the total number of publications written about "Spermidine" by people in this website by year, and whether "Spermidine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spermidine" by people in Profiles.
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Zayas-Santiago A, Malpica-Nieves CJ, R?os DS, D?az-Garc?a A, V?zquez PN, Santiago JM, Rivera-Aponte DE, Veh RW, M?ndez-Gonz?lez M, Eaton M, Skatchkov SN. Spermidine Synthase Localization in Retinal Layers: Early Age Changes. Int J Mol Sci. 2024 Jun 12; 25(12).
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Weiss T, Bernard R, Laube G, Rieck J, Eaton MJ, Skatchkov SN, Veh RW. As Verified with the Aid of Biotinylated Spermine, the Brain Cannot Take up Polyamines from the Bloodstream Leaving It Solely Dependent on Local Biosynthesis. Biomolecules. 2023 07 13; 13(7).
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Malpica-Nieves CJ, Rivera-Aponte DE, Tejeda-Bayron FA, Mayor AM, Phanstiel O, Veh RW, Eaton MJ, Skatchkov SN. The involvement of polyamine uptake and synthesis pathways in the proliferation of neonatal astrocytes. Amino Acids. 2020 Aug; 52(8):1169-1180.
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Lin YH, Romo JA, Smith TC, Reyes AN, Karna SLR, Miller CL, Van Laar TA, Yendapally R, Chambers JP, Seshu J. Spermine and Spermidine Alter Gene Expression and Antigenic Profile of Borrelia burgdorferi. Infect Immun. 2017 03; 85(3).
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Sala-Rabanal M, Li DC, Dake GR, Kurata HT, Inyushin M, Skatchkov SN, Nichols CG. Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3. Mol Pharm. 2013 Apr 01; 10(4):1450-8.
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Benedikt J, Inyushin M, Kucheryavykh YV, Rivera Y, Kucheryavykh LY, Nichols CG, Eaton MJ, Skatchkov SN. Intracellular polyamines enhance astrocytic coupling. Neuroreport. 2012 Dec 05; 23(17):1021-5.
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Puntambekar SS, Davis DS, Hawel L, Crane J, Byus CV, Carson MJ. LPS-induced CCL2 expression and macrophage influx into the murine central nervous system is polyamine-dependent. Brain Behav Immun. 2011 May; 25(4):629-39.
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Pereira LS, Silva PI, Miranda MT, Almeida IC, Naoki H, Konno K, Daffre S. Structural and biological characterization of one antibacterial acylpolyamine isolated from the hemocytes of the spider Acanthocurria gomesiana. Biochem Biophys Res Commun. 2007 Jan 26; 352(4):953-9.
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Mittal MK, Misra S, Owais M, Goyal N. Expression, purification, and characterization of Leishmania donovani trypanothione reductase in Escherichia coli. Protein Expr Purif. 2005 Apr; 40(2):279-86.
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von Deutsch DA, Abukhalaf IK, Wineski LE, Silvestrov NA, Bayorh MA, Potter DE. Changes in muscle proteins and spermidine content in response to unloading and clenbuterol treatment. Can J Physiol Pharmacol. 2003 Jan; 81(1):28-39.