The relationship between duration of initial alcohol exposure and persistence of molecular tolerance is markedly nonlinear.
Vel?zquez-Marrero C, Wynne P, Bernardo A, Palacio S, Martin G, Treistman SN. The relationship between duration of initial alcohol exposure and persistence of molecular tolerance is markedly nonlinear. J Neurosci. 2011 Feb 16; 31(7):2436-46.