Large-Conductance Calcium-Activated Potassium Channels
"Large-Conductance Calcium-Activated Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.
| Descriptor ID |
D051036
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| MeSH Number(s) |
D12.776.157.530.400.600.150.500 D12.776.543.550.450.750.150.500 D12.776.543.585.400.750.150.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Large-Conductance Calcium-Activated Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Large-Conductance Calcium-Activated Potassium Channels".
This graph shows the total number of publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in this website by year, and whether "Large-Conductance Calcium-Activated Potassium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 4 | 0 | 4 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Large-Conductance Calcium-Activated Potassium Channels" by people in Profiles.
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Cordero Padilla K, Monefeldt GA, Guev?rez Gal?n A, Marrero HG, Lloret-Torres ME, Vel?zquez-Marrero C. BK ZERO isoform HEK293 stably transfected cell lines differing 3'UTRs to assess miR-9 regulation. PLoS One. 2024; 19(3):e0298966.
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Jaffe DB, Brenner R. A computational model for how the fast afterhyperpolarization paradoxically increases gain in regularly firing neurons. J Neurophysiol. 2018 04 01; 119(4):1506-1520.
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Whitmire LE, Ling L, Bugay V, Carver CM, Timilsina S, Chuang HH, Jaffe DB, Shapiro MS, Cavazos JE, Brenner R. Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule neurons following seizure activity. PLoS One. 2017; 12(11):e0188064.
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Vel?zquez-Marrero C, Burgos A, Garc?a JO, Palacio S, Marrero HG, Bernardo A, P?rez-Laspiur J, Rivera-Oliver M, Seale G, Treistman SN. Alcohol Regulates BK Surface Expression via Wnt/?-Catenin Signaling. J Neurosci. 2016 10 12; 36(41):10625-10639.
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Palacio S, Vel?zquez-Marrero C, Marrero HG, Seale GE, Yudowski GA, Treistman SN. Time-Dependent Effects of Ethanol on BK Channel Expression and Trafficking in Hippocampal Neurons. Alcohol Clin Exp Res. 2015 Sep; 39(9):1619-31.
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Vel?squez-Mart?nez MC, V?zquez-Torres R, Rojas LV, Sanabria P, Jim?nez-Rivera CA. Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons. Neuropharmacology. 2015 Jan; 88:110-21.
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Takacs Z, Imredy JP, Bingham JP, Zhorov BS, Moczydlowski EG. Interaction of the BKCa channel gating ring with dendrotoxins. Channels (Austin). 2014; 8(5):421-32.
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Yuan C, Chen M, Covey DF, Johnston LJ, Treistman SN. Cholesterol tuning of BK ethanol response is enantioselective, and is a function of accompanying lipids. PLoS One. 2011; 6(11):e27572.
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Jaffe DB, Wang B, Brenner R. Shaping of action potentials by type I and type II large-conductance Ca?+-activated K+ channels. Neuroscience. 2011 Sep 29; 192:205-18.
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Seidel KN, Derst C, Salzmann M, H?ltje M, Priller J, Markgraf R, Heinemann SH, Heilmann H, Skatchkov SN, Eaton MJ, Veh RW, Pr?ss H. Expression of the voltage- and Ca2+-dependent BK potassium channel subunits BK?1 and BK?4 in rodent astrocytes. Glia. 2011 Jun; 59(6):893-902.