Heme Oxygenase (Decyclizing)
"Heme Oxygenase (Decyclizing)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin in the presence of molecular oxygen and reduced NADPH. The enzyme is induced by metals, particularly cobalt.
| Descriptor ID |
D006419
|
| MeSH Number(s) |
D08.811.682.690.708.410
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Heme Oxygenase (Decyclizing)".
Below are MeSH descriptors whose meaning is more specific than "Heme Oxygenase (Decyclizing)".
This graph shows the total number of publications written about "Heme Oxygenase (Decyclizing)" by people in this website by year, and whether "Heme Oxygenase (Decyclizing)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 2 | 2 | 4 |
| 2001 | 3 | 1 | 4 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heme Oxygenase (Decyclizing)" by people in Profiles.
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Kashfi K, Patel KK. Carbon monoxide and its role in human physiology: A brief historical perspective. Biochem Pharmacol. 2022 10; 204:115230.
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Ozurumba E, Mathew O, Ranganna K, Choi M, Oyekan A. Regulation of hypoxia inducible factor/prolyl hydroxylase binding domain proteins 1 by PPARa and high salt diet. J Basic Clin Physiol Pharmacol. 2018 Mar 28; 29(2):165-173.
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Liu F, Hu Q, Li B, Manaenko A, Chen Y, Tang J, Guo Z, Tang J, Zhang JH. Recombinant milk fat globule-EGF factor-8 reduces oxidative stress via integrin ?3/nuclear factor erythroid 2-related factor 2/heme oxygenase pathway in subarachnoid hemorrhage rats. Stroke. 2014 Dec; 45(12):3691-7.
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Davinelli S, Scapagnini G, Denaro F, Calabrese V, Benedetti F, Krishnan S, Curreli S, Bryant J, Zella D. Altered expression pattern of Nrf2/HO-1 axis during accelerated-senescence in HIV-1 transgenic rat. Biogerontology. 2014; 15(5):449-61.
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Christie AE, Fontanilla TM, Roncalli V, Cieslak MC, Lenz PH. Diffusible gas transmitter signaling in the copepod crustacean Calanus finmarchicus: identification of the biosynthetic enzymes of nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H2S) using a de novo assembled transcriptome. Gen Comp Endocrinol. 2014 Jun 01; 202:76-86.
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Ping Z, Liu W, Kang Z, Cai J, Wang Q, Cheng N, Wang S, Wang S, Zhang JH, Sun X. Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme. Brain Res. 2010 Jul 09; 1343:178-85.
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Paiva-Silva GO, Cruz-Oliveira C, Nakayasu ES, Maya-Monteiro CM, Dunkov BC, Masuda H, Almeida IC, Oliveira PL. A heme-degradation pathway in a blood-sucking insect. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8030-5.
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Dhulipala PD, Datta PK, Reddy ES, Lianos EA. Differential regulation of the rat heme oxygenase-1 expression by Ets oncoproteins in glomerular mesangial cells. J Lab Clin Med. 2005 Dec; 146(6):326-32.
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von Deutsch AW, Mitchell CD, Williams CE, Dutt K, Silvestrov NA, Klement BJ, Abukhalaf IK, von Deutsch DA. Polyamines protect against radiation-induced oxidative stress. Gravit Space Biol Bull. 2005 Jun; 18(2):109-10.
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Takeda A, Itoyama Y, Kimpara T, Zhu X, Avila J, Dwyer BE, Perry G, Smith MA. Heme catabolism and heme oxygenase in neurodegenerative disease. Antioxid Redox Signal. 2004 Oct; 6(5):888-94.