"DNA Polymerase III" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in E. coli and other lower organisms but may be present in higher organisms. Use also for a more complex form of DNA polymerase III designated as DNA polymerase III* or pol III* which is 15 times more active biologically than DNA polymerase I in the synthesis of DNA. This polymerase has both 3'-5' and 5'-3' exonuclease activities, is inhibited by sulfhydryl reagents, and has the same template-primer dependence as pol II. EC 2.7.7.7.
| Descriptor ID |
D004258
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| MeSH Number(s) |
D08.811.913.696.445.308.300.235
|
| Concept/Terms |
DNA Polymerase III- DNA Polymerase III
- Polymerase III, DNA
- DNA Pol III
- DNA Polymerase delta
- Polymerase delta, DNA
- DNA-Dependent DNA Polymerase III
- DNA Dependent DNA Polymerase III
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase III".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase III".
This graph shows the total number of publications written about "DNA Polymerase III" by people in this website by year, and whether "DNA Polymerase III" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1997 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Polymerase III" by people in Profiles.
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Jeruzalmi D. The partner-swapping sliding clamp loader exposed. Nat Struct Mol Biol. 2022 04; 29(4):283-286.
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Green M, Newell O, Aboyade-Cole A, Darling-Reed S, Thomas RD. Diallyl sulfide induces the expression of nucleotide excision repair enzymes in the breast of female ACI rats. Toxicol Lett. 2007 Jan 10; 168(1):40-4.
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Jeruzalmi D. The opened processivity clamp slides into view. Proc Natl Acad Sci U S A. 2005 Oct 18; 102(42):14939-40.
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Bruck I, Yuzhakov A, Yurieva O, Jeruzalmi D, Skangalis M, Kuriyan J, O'Donnell M. Analysis of a multicomponent thermostable DNA polymerase III replicase from an extreme thermophile. J Biol Chem. 2002 May 10; 277(19):17334-48.
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Mocz G, Gibbons IR. Model for the motor component of dynein heavy chain based on homology to the AAA family of oligomeric ATPases. Structure. 2001 Feb 07; 9(2):93-103.
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Kamel D, Mackey ZB, Sj?blom T, Walter CA, McCarrey JR, Uitto L, Palosaari H, L?hdetie J, Tomkinson AE, Syv?oja JE. Role of deoxyribonucleic acid polymerase epsilon in spermatogenesis in mice. Biol Reprod. 1997 Dec; 57(6):1367-74.
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Torres-Ramos CA, Prakash S, Prakash L. Requirement of yeast DNA polymerase delta in post-replicational repair of UV-damaged DNA. J Biol Chem. 1997 Oct 10; 272(41):25445-8.
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Flores-Rozas H, Kelman Z, Dean FB, Pan ZQ, Harper JW, Elledge SJ, O'Donnell M, Hurwitz J. Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18):8655-9.
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Gerschenson M, Low RL, Loehr J. Levels of the mitochondrial endonuclease during rat cardiac development implicate a role for the enzyme in repair of oxidative damage in mitochondrial DNA. J Mol Cell Cardiol. 1994 Jan; 26(1):31-40.
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Houmiel KL, Gerschenson M, Low RL. Mitochondrial endonuclease activity in the rat varies markedly among tissues in relation to the rate of tissue metabolism. Biochim Biophys Acta. 1991 Aug 30; 1079(2):197-202.