"DNA Polymerase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent DNA polymerase characterized in prokaryotes and may be present in higher organisms. It has both 3'-5' and 5'-3' exonuclease activity, but cannot use native double-stranded DNA as template-primer. It is not inhibited by sulfhydryl reagents and is active in both DNA synthesis and repair. EC 2.7.7.7.
| Descriptor ID |
D004256
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.225
|
| Concept/Terms |
DNA Polymerase I- DNA Polymerase I
- Polymerase I, DNA
- Klenow Fragment
- DNA-Dependent DNA Polymerase I
- DNA Dependent DNA Polymerase I
- DNA Pol I
- DNA Polymerase alpha
- Polymerase alpha, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Polymerase I".
Below are MeSH descriptors whose meaning is more specific than "DNA Polymerase I".
This graph shows the total number of publications written about "DNA Polymerase I" by people in this website by year, and whether "DNA Polymerase I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Polymerase I" by people in Profiles.
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El-Baba C, Ayache Z, Goli M, Hayar B, Kawtharani Z, Pisano C, Kobeissy F, Mechref Y, Darwiche N. The Antitumor Effect of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomics Approach. Int J Mol Sci. 2023 Sep 14; 24(18).
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Jurado LA, Drummond JT, Jarrett HW. Catalytic chromatography. Anal Biochem. 2000 Jun 15; 282(1):39-45.
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Lipinski LJ, Ross HL, Zajc B, Sayer JM, Jerina DM, Dipple A. Effect of single benzo[a]pyrene diol epoxide-deoxyguanosine adducts on the action of DNA polymerases in vitro. Int J Oncol. 1998 Aug; 13(2):269-73.
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Kamel D, Mackey ZB, Sj?blom T, Walter CA, McCarrey JR, Uitto L, Palosaari H, L?hdetie J, Tomkinson AE, Syv?oja JE. Role of deoxyribonucleic acid polymerase epsilon in spermatogenesis in mice. Biol Reprod. 1997 Dec; 57(6):1367-74.