"Antiprotozoal Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that are destructive to protozoans.
| Descriptor ID |
D000981
|
| MeSH Number(s) |
D27.505.954.122.250.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Antiprotozoal Agents".
Below are MeSH descriptors whose meaning is more specific than "Antiprotozoal Agents".
This graph shows the total number of publications written about "Antiprotozoal Agents" by people in this website by year, and whether "Antiprotozoal Agents" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 4 | 0 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 4 | 0 | 4 |
| 2018 | 1 | 2 | 3 |
| 2020 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 1 | 2 |
| 2025 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Antiprotozoal Agents" by people in Profiles.
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Okafor EO, Bella-Omunagbe M, Elugbadebo T, Dokunmu TM, Adebiyi E. Targeting invasion-associated proteins PfSUB2 and PfTRAMP in Plasmodium falciparum: identification of potential inhibitors via molecular docking. BMC Infect Dis. 2025 Aug 19; 25(1):1038.
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Iniguez E, Rodriguez F, Husseneder C, Foil L, Maldonado RA. Ligand-lytic peptides for specific targeting of Leishmania major and Trypanosoma cruzi parasites. Front Cell Infect Microbiol. 2025; 15:1595333.
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VanKoten HW, Pence BC, Klinkenberg JR, Das S, Patterson SE. Synthesis and evaluation of anti-Giardia activity of oseltamivir analogs. Bioorg Med Chem Lett. 2025 Feb 01; 116:130035.
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Manciu FS, Guerrero J, Pence BC, Martinez Lopez LV, Das S. Assessment of Drug Activities against Giardia Using Hyperspectral Raman Microscopy. Pathogens. 2024 Apr 27; 13(5).
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Santos CC, Zhang H, Batista MM, de Oliveira GM, Demarque KC, da Silva NL, Moreira OC, Ogungbe IV, Soeiro MNC. Phenotypic investigation of 4-nitrophenylacetyl- and 4-nitro-1H-imidazoyl-based compounds as antileishmanial agents. Parasitology. 2022 04; 149(4):490-495.
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Santos CC, Zhang H, Batista MM, de Oliveira GM, Demarque KC, da Silva-Gomes NL, Moreira OC, Ogungbe IV, Soeiro MNC. In Vitro and In Vivo Evaluation of an Adamantyl-Based Phenyl Sulfonyl Acetamide against Cutaneous Leishmaniasis Models of Leishmania amazonensis. Antimicrob Agents Chemother. 2020 11 17; 64(12).
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Rodriguez F, John SF, Iniguez E, Montalvo S, Michael K, White L, Liang D, Olaleye OA, Maldonado RA. In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors. Antimicrob Agents Chemother. 2020 05 21; 64(6).
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Zhang H, Collins J, Nyamwihura R, Crown O, Ajayi O, Ogungbe IV. Vinyl sulfone-based inhibitors of trypanosomal cysteine protease rhodesain with improved antitrypanosomal activities. Bioorg Med Chem Lett. 2020 07 15; 30(14):127217.
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Friggeri L, Hargrove TY, Rachakonda G, Blobaum AL, Fisher P, de Oliveira GM, da Silva CF, Soeiro MNC, Nes WD, Lindsley CW, Villalta F, Guengerich FP, Lepesheva GI. Sterol 14a-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae. J Med Chem. 2018 12 13; 61(23):10910-10921.
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Zhou W, Debnath A, Jennings G, Hahn HJ, Vanderloop BH, Chaudhuri M, Nes WD, Podust LM. Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. PLoS Pathog. 2018 09; 14(9):e1007245.