Antimalarials

"Antimalarials" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)

Descriptor ID	D000962
MeSH Number(s)	D27.505.954.122.250.100.085
Concept/Terms	Antimalarials Antimalarials Antimalarial Agents Agents, Antimalarial Antimalarial Drugs Drugs, Antimalarial Anti-Malarials Anti Malarials

Below are MeSH descriptors whose meaning is more general than "Antimalarials".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Therapeutic Uses [D27.505.954]
Anti-Infective Agents [D27.505.954.122]
Antiparasitic Agents [D27.505.954.122.250]
Antiprotozoal Agents [D27.505.954.122.250.100]
Antimalarials [D27.505.954.122.250.100.085]

Below are MeSH descriptors whose meaning is related to "Antimalarials".

Below are MeSH descriptors whose meaning is more specific than "Antimalarials".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antimalarials" by people in this website by year, and whether "Antimalarials" was a major or minor topic of these publications.

Bar chart showing 45 publications over 21 distinct years, with a maximum of 5 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2000	0	1	1
2002	1	0	1
2004	2	1	3
2006	0	1	1
2008	0	1	1
2009	2	1	3
2010	2	0	2
2011	4	0	4
2012	1	0	1
2013	2	0	2
2014	4	0	4
2015	3	1	4
2016	2	2	4
2017	1	0	1
2018	0	1	1
2019	1	1	2
2020	2	0	2
2021	1	0	1
2022	1	0	1
2024	5	0	5

Below are the most recent publications written about "Antimalarials" by people in Profiles.

Nie Z, Bonnert R, Tsien J, Deng X, Higgs C, El Mazouni F, Zhang X, Li R, Ho N, Feher V, Paulsen J, Shackleford DM, Katneni K, Chen G, Ng ACF, McInerney M, Wang W, Saunders J, Collins D, Yan D, Li P, Campbell M, Patil R, Ghoshal A, Mondal P, Kundu A, Chittimalla R, Mahadeva M, Kokkonda S, White J, Das R, Mukherjee P, Angulo-Barturen I, Jim?nez-D?az MB, Malmstrom R, Lawrenz M, Rodriguez-Granillo A, Rathod PK, Tomchick DR, Palmer MJ, Laleu B, Qin T, Charman SA, Phillips MA. Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention. J Med Chem. 2025 01 09; 68(1):590-637.

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Rosado-Qui?ones AM, Col?n-Lorenzo EE, Pala ZR, Bosch J, Kudyba K, Kudyba H, Leed SE, Roncal N, Baerga-Ortiz A, Roche-Lima A, Gerena Y, Fidock DA, Roth A, Vega-Rodr?guez J, Serrano AE. Novel hydrazone compounds with broad-spectrum antiplasmodial activity and synergistic interactions with antimalarial drugs. Antimicrob Agents Chemother. 2024 06 05; 68(6):e0164323.

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van Schalkwyk DA, Pratt S, Nolder D, Stewart LB, Liddy H, Muwanguzi-Karugaba J, Beshir KB, Britten D, Victory E, Rogers C, Millard J, Brown M, Nabarro LE, Taylor A, Young BC, Chiodini PL, Sutherland CJ. Treatment Failure in a UK Malaria Patient Harboring Genetically Variant Plasmodium falciparum From Uganda With Reduced In Vitro Susceptibility to Artemisinin and Lumefantrine. Clin Infect Dis. 2024 02 17; 78(2):445-452.

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Upadhyay DB, Mokariya JA, Patel PJ, Patel SG, Das A, Nandi A, Nogales J, More N, Kumar A, Rajani DP, Narayan M, Kumar J, Banerjee S, Sahoo SK, Patel HM. Indole clubbed 2,4-thiazolidinedione linked 1,2,3-triazole as a potent antimalarial and antibacterial agent against drug-resistant strain and molecular modeling studies. Arch Pharm (Weinheim). 2024 Apr; 357(4):e2300673.

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Roche-Lima A, Rosado-Qui?ones AM, Feliu-Maldonado RA, Figueroa-Gispert MDM, D?az-Rivera J, D?az-Gonz?lez RG, Carrasquillo-Carrion K, Nieves BG, Col?n-Lorenzo EE, Serrano AE. Antimalarial Drug Combination Predictions Using the Machine Learning Synergy Predictor (MLSyPred?) tool. Acta Parasitol. 2024 Mar; 69(1):415-425.

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Olaleye OA, Zash R, Diseko M, Mayondi G, Mabuta J, Lockman S, Melton ML, Mmalane M, Makhema J, Shapiro RL. Impact of prophylactic antimalarials in pregnant women living with Human Immunodeficiency Virus?on birth outcomes in Botswana. Trop Med Int Health. 2022 11; 27(11):990-998.

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Nyamwihura RJ, Zhang H, Collins JT, Crown O, Ogungbe IV. Nopol-Based Quinoline Derivatives as Antiplasmodial Agents. Molecules. 2021 Feb 14; 26(4).

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Diaby V, Almutairi RD, Chen Z, Moussa RK, Berthe A. A pharmacovigilance study to quantify the strength of association between the combination of antimalarial drugs and azithromycin and cardiac arrhythmias: implications for the treatment of COVID-19. Expert Rev Pharmacoecon Outcomes Res. 2021 Feb; 21(1):159-168.

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Hosseini-Zare MS, Sarhadi M, Zarei M, Thilagavathi R, Selvam C. Synergistic effects of curcumin and its analogs with other bioactive compounds: A comprehensive review. Eur J Med Chem. 2021 Jan 15; 210:113072.

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Hsia SH, Duran P, Lee ML, Davidson MB. Randomized controlled trial comparing hydroxychloroquine with pioglitazone as third-line agents in type 2 diabetic patients failing metformin plus a sulfonylurea: A pilot study. J Diabetes. 2020 Jan; 12(1):91-94.

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