Heme

"Heme" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.

Descriptor ID	D006418
MeSH Number(s)	D03.383.129.578.840.500.640.587 D03.633.400.909.500.640.587 D04.345.783.500.640.587 D23.767.727.640.587
Concept/Terms	Heme Heme Haem Protoheme Protoheme IX Ferroprotoporphyrin Heme b

Below are MeSH descriptors whose meaning is more general than "Heme".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Pyrroles [D03.383.129.578]
Tetrapyrroles [D03.383.129.578.840]
Porphyrins [D03.383.129.578.840.500]
Metalloporphyrins [D03.383.129.578.840.500.640]
Heme [D03.383.129.578.840.500.640.587]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 4 or More Rings [D03.633.400]
Tetrapyrroles [D03.633.400.909]
Porphyrins [D03.633.400.909.500]
Metalloporphyrins [D03.633.400.909.500.640]
Heme [D03.633.400.909.500.640.587]
Polycyclic Compounds [D04]
Macrocyclic Compounds [D04.345]
Tetrapyrroles [D04.345.783]
Porphyrins [D04.345.783.500]
Metalloporphyrins [D04.345.783.500.640]
Heme [D04.345.783.500.640.587]
Biological Factors [D23]
Pigments, Biological [D23.767]
Porphyrins [D23.767.727]
Metalloporphyrins [D23.767.727.640]
Heme [D23.767.727.640.587]

Below are MeSH descriptors whose meaning is related to "Heme".

Below are MeSH descriptors whose meaning is more specific than "Heme".

Heme
Hemin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Heme" by people in this website by year, and whether "Heme" was a major or minor topic of these publications.

Bar chart showing 60 publications over 25 distinct years, with a maximum of 7 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2000	1	0	1
2001	0	1	1
2002	1	0	1
2003	3	2	5
2004	3	4	7
2005	2	3	5
2006	1	0	1
2007	2	0	2
2008	1	2	3
2009	1	2	3
2010	1	0	1
2011	3	0	3
2012	1	0	1
2013	2	3	5
2014	1	0	1
2015	3	1	4
2016	2	0	2
2018	3	0	3
2019	0	2	2
2020	0	1	1
2021	0	1	1
2022	0	3	3
2023	0	2	2
2025	1	0	1

Below are the most recent publications written about "Heme" by people in Profiles.

Agbozo WK, Solomon W, Lekpor CE, Erskine IJ, Oguljahan B, Bashi A, Harbuzariu A, Driss A, Adjei S, Paemka L, Ofori-Acquah SF, Stiles JK. Hydroxyurea Mitigates Heme-Induced Inflammation and Kidney Injury in Humanized Sickle Cell Mice. Int J Mol Sci. 2025 Mar 30; 26(7).

View in: PubMed
Bashi A, Lekpor C, Hood JL, Thompson WE, Stiles JK, Driss A. Modulation of Heme-Induced Inflammation Using MicroRNA-Loaded Liposomes: Implications for Hemolytic Disorders Such as Malaria and Sickle Cell Disease. Int J Mol Sci. 2023 Nov 29; 24(23).

View in: PubMed
Zhang L, Brown MC, Mutter AC, Greenland KN, Cooley JW, Koder RL. Protein dynamics govern the oxyferrous state lifetime of an artificial oxygen transport protein. Biophys J. 2023 11 21; 122(22):4440-4450.

View in: PubMed
Thomas JJ, Harp KO, Bashi A, Hood JL, Botchway F, Wilson MD, Thompson WE, Stiles JK, Driss A. MiR-451a and let-7i-5p loaded extracellular vesicles attenuate heme-induced inflammation in hiPSC-derived endothelial cells. Front Immunol. 2022; 13:1082414.

View in: PubMed
Chambliss C, Stiles JK, Gee BE. Neuregulin-1 attenuates hemolysis- and ischemia induced-cerebrovascular inflammation associated with sickle cell disease. J Stroke Cerebrovasc Dis. 2023 Feb; 32(2):106912.

View in: PubMed
Ch'ng JH, Muthu M, Chong KKL, Wong JJ, Tan CAZ, Koh ZJS, Lopez D, Matysik A, Nair ZJ, Barkham T, Wang Y, Kline KA. Heme cross-feeding can augment Staphylococcus aureus and Enterococcus faecalis dual species biofilms. ISME J. 2022 08; 16(8):2015-2026.

View in: PubMed
Nti AM, Botchway F, Salifu H, Cespedes JC, Harbuzariu A, Onyekaba J, Chambliss C, Liu M, Adjei A, Jolly P, Stiles JK. Effects of Iron Supplements on Heme Scavengers in Pregnancy. Am J Trop Med Hyg. 2021 09 27; 105(5):1163-1172.

View in: PubMed
Loth MK, Guariglia SR, Re DB, Perez J, de Paiva VN, Dziedzic JL, Chambers JW, Azzam DJ, Guilarte TR. A Novel Interaction of Translocator Protein 18?kDa (TSPO) with NADPH Oxidase in Microglia. Mol Neurobiol. 2020 Nov; 57(11):4467-4487.

View in: PubMed
Harbuzariu A, Pitts S, Cespedes JC, Harp KO, Nti A, Shaw AP, Liu M, Stiles JK. Modelling heme-mediated brain injury associated with cerebral malaria in human brain cortical organoids. Sci Rep. 2019 12 16; 9(1):19162.

View in: PubMed
Wiel C, Le Gal K, Ibrahim MX, Jahangir CA, Kashif M, Yao H, Ziegler DV, Xu X, Ghosh T, Mondal T, Kanduri C, Lindahl P, Sayin VI, Bergo MO. BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis. Cell. 2019 07 11; 178(2):330-345.e22.

View in: PubMed

People

Explore

Similar Concepts

Top Journals