Porphyrins

"Porphyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.

Descriptor ID	D011166
MeSH Number(s)	D03.383.129.578.840.500 D03.633.400.909.500 D04.345.783.500 D23.767.727
Concept/Terms	Porphyrins Porphyrins

Below are MeSH descriptors whose meaning is more general than "Porphyrins".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Azoles [D03.383.129]
Pyrroles [D03.383.129.578]
Tetrapyrroles [D03.383.129.578.840]
Porphyrins [D03.383.129.578.840.500]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 4 or More Rings [D03.633.400]
Tetrapyrroles [D03.633.400.909]
Porphyrins [D03.633.400.909.500]
Polycyclic Compounds [D04]
Macrocyclic Compounds [D04.345]
Tetrapyrroles [D04.345.783]
Porphyrins [D04.345.783.500]
Biological Factors [D23]
Pigments, Biological [D23.767]
Porphyrins [D23.767.727]

Below are MeSH descriptors whose meaning is related to "Porphyrins".

Below are MeSH descriptors whose meaning is more specific than "Porphyrins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Porphyrins" by people in this website by year, and whether "Porphyrins" was a major or minor topic of these publications.

Bar chart showing 48 publications over 20 distinct years, with a maximum of 5 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2002	3	1	4
2004	2	0	2
2005	1	0	1
2006	2	1	3
2007	4	0	4
2008	3	0	3
2009	4	1	5
2010	2	0	2
2011	2	1	3
2012	1	0	1
2013	3	0	3
2014	1	0	1
2015	2	0	2
2016	2	1	3
2017	4	0	4
2018	3	0	3
2019	1	0	1
2020	1	0	1
2024	0	1	1

Below are the most recent publications written about "Porphyrins" by people in Profiles.

Umar S, Samokhvalov A. Encapsulation of Gemcitabine on Porphyrin Aluminum Metal-Organic Framework by Mechano-Chemistry, Delayed Drug Release and Cytotoxicity to Pancreatic Cancer PANC-1 Cells. Molecules. 2024 Jul 04; 29(13).

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Hern?ndez-Gil J, Lewis JS, Reiner T, Drain CM, Gonzales J. Leveraging synthetic chlorins for bio-imaging applications. Chem Commun (Camb). 2020 Oct 20; 56(83):12608-12611.

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Singh S, Aggarwal A, Bhupathiraju NVSDK, Jovanovic IR, Landress M, Tuz MP, Gao R, Drain CM. Comparing a thioglycosylated chlorin and phthalocyanine as potential theranostic agents. Bioorg Med Chem. 2020 02 01; 28(3):115259.

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Gonzales J, Bhupathiraju NVSDK, Hart D, Yuen M, Sifuentes MP, Samarxhiu B, Maranan M, Berisha N, Batteas J, Drain CM. One-Pot Synthesis of Four Chlorin Derivatives by a Divergent Ylide. J Org Chem. 2018 06 15; 83(12):6307-6314.

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Johnson CN, Gorbet GE, Ramsower H, Urquidi J, Brancaleon L, Demeler B. Multi-wavelength analytical ultracentrifugation of human serum albumin complexed with porphyrin. Eur Biophys J. 2018 Oct; 47(7):789-797.

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Pereira PMR, Rizvi W, Bhupathiraju NVSDK, Berisha N, Fernandes R, Tom? JPC, Drain CM. Carbon-1 versus Carbon-3 Linkage of d-Galactose to Porphyrins: Synthesis, Uptake, and Photodynamic Efficiency. Bioconjug Chem. 2018 02 21; 29(2):306-315.

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Wen Y, Zhang W, Gong N, Wang YF, Guo HB, Guo W, Wang PC, Liang XJ. Carrier-free, self-assembled pure drug nanorods composed of 10-hydroxycamptothecin and chlorin e6 for combinatorial chemo-photodynamic antitumor therapy in vivo. Nanoscale. 2017 Oct 05; 9(38):14347-14356.

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Farley C, Aggarwal A, Singh S, Dolor A, To P, Falber A, Crossley M, Drain CM. A Structural Model of Nitro-Porphyrin Dyes Based on Spectroscopy and Density Functional Theory. J Comput Chem. 2018 07 05; 39(18):1129-1142.

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Pereira PMR, Berisha N, Bhupathiraju NVSDK, Fernandes R, Tom? JPC, Drain CM. Cancer cell spheroids are a better screen for the photodynamic efficiency of glycosylated photosensitizers. PLoS One. 2017; 12(5):e0177737.

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Gonzales J, Bhupathiraju NV, Perea W, Chu H, Berisha N, Bueno V, Dodic N, Rozenberg J, Greenbaum NL, Drain CM. Facile synthesis of chlorin bioconjugates by a series of click reactions. Chem Commun (Camb). 2017 Mar 28; 53(26):3773-3776.

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