Malaria, Falciparum

"Malaria, Falciparum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Descriptor ID	D016778
MeSH Number(s)	C03.752.530.650
Concept/Terms	Malaria, Falciparum Malaria, Falciparum Plasmodium falciparum Malaria Malaria, Plasmodium falciparum

Below are MeSH descriptors whose meaning is more general than "Malaria, Falciparum".

Diseases [C]
Parasitic Diseases [C03]
Protozoan Infections [C03.752]
Malaria [C03.752.530]
Malaria, Falciparum [C03.752.530.650]

Below are MeSH descriptors whose meaning is related to "Malaria, Falciparum".

Below are MeSH descriptors whose meaning is more specific than "Malaria, Falciparum".

Malaria, Falciparum
Blackwater Fever

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Malaria, Falciparum" by people in this website by year, and whether "Malaria, Falciparum" was a major or minor topic of these publications.

Bar chart showing 69 publications over 25 distinct years, with a maximum of 6 publications in 2010 and 2015 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1999	1	0	1
2000	1	0	1
2001	1	0	1
2002	0	2	2
2003	1	0	1
2004	0	2	2
2005	2	0	2
2007	1	0	1
2008	3	2	5
2009	3	1	4
2010	5	1	6
2011	4	0	4
2012	3	0	3
2013	2	1	3
2015	6	0	6
2016	3	0	3
2017	5	1	6
2018	3	0	3
2019	3	0	3
2020	2	1	3
2022	2	0	2
2023	2	0	2
2024	1	2	3
2025	0	1	1

Below are the most recent publications written about "Malaria, Falciparum" by people in Profiles.

Okafor EO, Bella-Omunagbe M, Elugbadebo T, Dokunmu TM, Adebiyi E. Targeting invasion-associated proteins PfSUB2 and PfTRAMP in Plasmodium falciparum: identification of potential inhibitors via molecular docking. BMC Infect Dis. 2025 Aug 19; 25(1):1038.

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Nie Z, Bonnert R, Tsien J, Deng X, Higgs C, El Mazouni F, Zhang X, Li R, Ho N, Feher V, Paulsen J, Shackleford DM, Katneni K, Chen G, Ng ACF, McInerney M, Wang W, Saunders J, Collins D, Yan D, Li P, Campbell M, Patil R, Ghoshal A, Mondal P, Kundu A, Chittimalla R, Mahadeva M, Kokkonda S, White J, Das R, Mukherjee P, Angulo-Barturen I, Jim?nez-D?az MB, Malmstrom R, Lawrenz M, Rodriguez-Granillo A, Rathod PK, Tomchick DR, Palmer MJ, Laleu B, Qin T, Charman SA, Phillips MA. Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention. J Med Chem. 2025 01 09; 68(1):590-637.

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van Schalkwyk DA, Pratt S, Nolder D, Stewart LB, Liddy H, Muwanguzi-Karugaba J, Beshir KB, Britten D, Victory E, Rogers C, Millard J, Brown M, Nabarro LE, Taylor A, Young BC, Chiodini PL, Sutherland CJ. Treatment Failure in a UK Malaria Patient Harboring Genetically Variant Plasmodium falciparum From Uganda With Reduced In Vitro Susceptibility to Artemisinin and Lumefantrine. Clin Infect Dis. 2024 02 17; 78(2):445-452.

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Roche-Lima A, Rosado-Qui?ones AM, Feliu-Maldonado RA, Figueroa-Gispert MDM, D?az-Rivera J, D?az-Gonz?lez RG, Carrasquillo-Carrion K, Nieves BG, Col?n-Lorenzo EE, Serrano AE. Antimalarial Drug Combination Predictions Using the Machine Learning Synergy Predictor (MLSyPred?) tool. Acta Parasitol. 2024 Mar; 69(1):415-425.

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Kayatani AKK, Bobbili N, Megnekou R, Matsunaga M, Leke RFG, Taylor DW. Are high avidity antibodies to Plasmodium falciparum antigens preferentially transferred across the placenta of premature and term babies? Placenta. 2023 09 07; 140:11-19.

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Shekhar S, Verma S, Gupta MK, Roy SS, Kaur I, Krishnamachari A, Dhar SK. Genome-wide binding sites of Plasmodium falciparum mini chromosome maintenance protein MCM6 show new insights into parasite DNA replication. Biochim Biophys Acta Mol Cell Res. 2023 10; 1870(7):119546.

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Tassi Yunga S, Siriwardhana C, Fouda GG, Bobbili N, Sama G, Chen JJ, Leke RFG, Taylor DW. Characterization of the primary antibody response to Plasmodium falciparum antigens in infants living in a malaria-endemic area. Malar J. 2022 Nov 19; 21(1):346.

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Kayatani AKK, Leke RGF, Leke RIJ, Fogako J, Taylor DW. Transplacental transfer of total immunoglobulin G and antibodies to Plasmodium falciparum antigens between the 24th week of gestation and term. Sci Rep. 2022 11 07; 12(1):18864.

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Harp KO, Botchway F, Dei-Adomakoh Y, Wilson MD, Hood JL, Adjei AA, Stiles JK, Driss A. Hemoglobin Genotypes Modulate Inflammatory Response to Plasmodium Infection. Front Immunol. 2020; 11:593546.

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Taylor AJ, Talwar D, Lee SJ, Cox L, Mayxay M, Newton PN. Comparison of Thiamin Diphosphate High-Performance Liquid Chromatography and Erythrocyte Transketolase Assays for Evaluating Thiamin Status in Malaria Patients without Beriberi. Am J Trop Med Hyg. 2020 12; 103(6):2600-2604.

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