Leishmania major

"Leishmania major" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals and causes cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) of the Old World. Transmission is by Phlebotomus sandflies.

Descriptor ID	D018320
MeSH Number(s)	B01.268.475.868.488.405
Concept/Terms	Leishmania major Leishmania major Leishmania majors majors, Leishmania Leishmania leishmania major Leishmania leishmania majors leishmania major, Leishmania major, Leishmania leishmania majors, Leishmania leishmania Leishmania (Leishmania) major Leishmania tropica major Leishmania tropica majors majors, Leishmania tropica tropica major, Leishmania tropica majors, Leishmania

Below are MeSH descriptors whose meaning is more general than "Leishmania major".

Organisms [B]
Eukaryota [B01]
Euglenozoa [B01.268]
Kinetoplastida [B01.268.475]
Trypanosomatina [B01.268.475.868]
Leishmania [B01.268.475.868.488]
Leishmania major [B01.268.475.868.488.405]

Below are MeSH descriptors whose meaning is related to "Leishmania major".

Below are MeSH descriptors whose meaning is more specific than "Leishmania major".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leishmania major" by people in this website by year, and whether "Leishmania major" was a major or minor topic of these publications.

Bar chart showing 18 publications over 13 distinct years, with a maximum of 2 publications in 2003 and 2010 and 2013 and 2015 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	1	2
2004	1	0	1
2005	1	0	1
2006	1	0	1
2008	1	0	1
2010	2	0	2
2012	1	0	1
2013	2	0	2
2014	0	1	1
2015	2	0	2
2016	0	1	1
2017	1	0	1
2018	1	1	2

Below are the most recent publications written about "Leishmania major" by people in Profiles.

Rodriguez F, Iniguez E, Pena Contreras G, Ahmed H, Costa TEMM, Skouta R, Maldonado RA. Development of Thiophene Compounds as Potent Chemotherapies for the Treatment of Cutaneous Leishmaniasis Caused by Leishmania major. Molecules. 2018 07 04; 23(7).

View in: PubMed
Subramaniam KS, Austin V, Schocker NS, Montoya AL, Anderson MS, Ashmus RA, Mesri M, Al-Salem W, Almeida IC, Michael K, Acosta-Serrano A. Anti-a-Gal antibodies detected by novel neoglycoproteins as a diagnostic tool for Old World cutaneous leishmaniasis caused by Leishmania major. Parasitology. 2018 11; 145(13):1758-1764.

View in: PubMed
Iniguez E, Schocker NS, Subramaniam K, Portillo S, Montoya AL, Al-Salem WS, Torres CL, Rodriguez F, Moreira OC, Acosta-Serrano A, Michael K, Almeida IC, Maldonado RA. An a-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major. PLoS Negl Trop Dis. 2017 Oct; 11(10):e0006039.

View in: PubMed
Iniguez E, Varela-Ramirez A, Mart?nez A, Torres CL, S?nchez-Delgado RA, Maldonado RA. Ruthenium-Clotrimazole complex has significant efficacy in the murine model of cutaneous leishmaniasis. Acta Trop. 2016 Dec; 164:402-410.

View in: PubMed
Iniguez EA, Perez A, Maldonado RA, Skouta R. Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania major. Bioorg Med Chem Lett. 2015 Nov 15; 25(22):5315-20.

View in: PubMed
Vasquez MA, Iniguez E, Das U, Beverley SM, Herrera LJ, Dimmock JR, Maldonado RA. Evaluation of a,?-unsaturated ketones as antileishmanial agents. Antimicrob Agents Chemother. 2015; 59(6):3598-601.

View in: PubMed
Al-Salem WS, Ferreira DM, Dyer NA, Alyamani EJ, Balghonaim SM, Al-Mehna AY, Al-Zubiany S, Ibrahim el-K, Al Shahrani AM, Alkhuailed H, Aldahan MA, Al Jarallh AM, Abdelhady SS, Al-Zahrani MH, Almeida IC, Acosta-Serrano A. Detection of high levels of anti-a-galactosyl antibodies in sera of patients with Old World cutaneous leishmaniasis: a possible tool for diagnosis and biomarker for cure in an elimination setting. Parasitology. 2014 Dec; 141(14):1898-903.

View in: PubMed
Ogungbe IV, Ng JD, Setzer WN. Interactions of antiparasitic alkaloids with Leishmania protein targets: a molecular docking analysis. Future Med Chem. 2013 Oct; 5(15):1777-99.

View in: PubMed
Iniguez E, S?nchez A, Vasquez MA, Mart?nez A, Olivas J, Sattler A, S?nchez-Delgado RA, Maldonado RA. Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cells. J Biol Inorg Chem. 2013 Oct; 18(7):779-90.

View in: PubMed
Mart?nez A, Carreon T, Iniguez E, Anzellotti A, S?nchez A, Tyan M, Sattler A, Herrera L, Maldonado RA, S?nchez-Delgado RA. Searching for new chemotherapies for tropical diseases: ruthenium-clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma cruzi and low toxicity toward normal mammalian cells. J Med Chem. 2012 Apr 26; 55(8):3867-77.

View in: PubMed

People

Explore

Similar Concepts

Top Journals