TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis.

Yang H, Bocchetta M, Kroczynska B, Elmishad AG, Chen Y, Liu Z, Bubici C, Mossman BT, Pass HI, Testa JR, Franzoso G, Carbone M. TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10397-10402.

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subject areas

Asbestos
Cell Transformation, Neoplastic
Cells, Cultured
Chromosomes, Human
Epithelium
Humans
Metaphase
NF-kappa B
Receptors, Tumor Necrosis Factor, Type I
RNA Interference
Signal Transduction
Tumor Necrosis Factor-alpha

authors with profiles

Michele Carbone, MD, PhD.

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