Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.

Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB. Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice. J Am Soc Nephrol. 2006 Jul; 17(7):1962-9.

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subject areas

Animals
Collagen Type IV
Disease Models, Animal
Glomerular Basement Membrane
Kidney Glomerulus
Mice
Mice, Transgenic
Nephritis, Hereditary
Protein Isoforms
Survival
X Chromosome

authors with profiles

Dorin-Bogdan Borza

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