A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells.

Arva NC, Gopen TR, Talbott KE, Campbell LE, Chicas A, White DE, Bond GL, Levine AJ, Bargonetti J. A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells. J Biol Chem. 2005 Jul 22; 280(29):26776-87.

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subject areas

Antineoplastic Agents
Cell Line, Tumor
Chromatin
Homozygote
Humans
Nuclear Proteins
Phosphorylation
Polymorphism, Single Nucleotide
Protein Binding
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-mdm2
Transcriptional Activation
Tumor Suppressor Protein p53

authors with profiles

Jill Bargonetti

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