Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C.

Kavetsky L, Green KK, Boyle BR, Yousufzai FAK, Padron ZM, Melli SE, Kuhnel VL, Jackson HM, Blanco RE, Howell GR, Soto I. Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C. Sci Rep. 2019 10 11; 9(1):14722.

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subject areas

Animals
Cerebellum
Dendrites
Disease Models, Animal
Female
Intracellular Signaling Peptides and Proteins
Male
Mice
Mice, Inbred C57BL
Mice, Transgenic
Microglia
Motor Activity
Nerve Degeneration
Niemann-Pick Disease, Type C
Phagocytosis
Phagosomes
Purkinje Cells

authors with profiles

Rosa E. Blanco

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