Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs.

Agrawal M, Saraf S, Saraf S, Antimisiaris SG, Chougule MB, Shoyele SA, Alexander A. Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs. J Control Release. 2018 07 10; 281:139-177.

View in: PubMed

subject areas

Administration, Intranasal
Alzheimer Disease
Animals
Biological Availability
Blood-Brain Barrier
Brain
Deferoxamine
Drug Carriers
Galantamine
Humans
Mucociliary Clearance
Nanoparticles
Nasal Mucosa
Nose
Olfactory Bulb
Risperidone
Tissue Distribution

authors with profiles

Mahavir Chougule, PhD, MPharm, B Pharm

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support