Tissue Distribution

"Tissue Distribution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.

Descriptor ID	D014018
MeSH Number(s)	G03.787.917 G07.690.725.949
Concept/Terms	Tissue Distribution Tissue Distribution Distribution, Tissue Distributions, Tissue Tissue Distributions

Below are MeSH descriptors whose meaning is more general than "Tissue Distribution".

Biological Sciences [G]
Metabolism [G03]
Pharmacokinetics [G03.787]
Tissue Distribution [G03.787.917]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacokinetics [G07.690.725]
Tissue Distribution [G07.690.725.949]

Below are MeSH descriptors whose meaning is related to "Tissue Distribution".

Below are MeSH descriptors whose meaning is more specific than "Tissue Distribution".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tissue Distribution" by people in this website by year, and whether "Tissue Distribution" was a major or minor topic of these publications.

Bar chart showing 156 publications over 29 distinct years, with a maximum of 13 publications in 2004

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
1994	1	1
1995	1	1
1997	1	1
1998	1	1
1999	6	6
2000	5	5
2001	7	7
2002	11	11
2003	8	8
2004	13	13
2005	4	4
2006	9	9
2007	7	7
2008	3	3
2009	6	6
2010	7	7
2011	8	8
2012	7	7
2013	7	7
2014	7	7
2015	9	9
2016	4	4
2017	4	4
2018	5	5
2019	4	4
2020	5	5
2021	2	2
2023	3	3
2024	1	1

Below are the most recent publications written about "Tissue Distribution" by people in Profiles.

Kaur G, Khanna B, Yusuf M, Sharma A, Khajuria A, Alajangi HK, Jaiswal PK, Sachdeva M, Barnwal RP, Singh G. A Path of Novelty from Nanoparticles to Nanobots: Theragnostic Approach for Targeting Cancer Therapy. Crit Rev Ther Drug Carrier Syst. 2024; 41(4):1-38.

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Etim I, Abasifreke B, Sun R, Kuddabujja D, Liang D, Du T, Gao S. Development of a novel UPLC-MS/MS method for the simultaneous quantification of mycophenolic mofetil, mycophenolic acid, and its major metabolites: Application to pharmacokinetic and tissue distribution study in rats. J Pharm Biomed Anal. 2023 Sep 20; 234:115504.

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Parker CC, Bin Salam A, Song PN, Gallegos C, Hunt A, Yates C, Jaynes J, Lopez H, Massicano AVF, Sorace AG, Fernandez S, Houson HA, Lapi SE. Evaluation of a CD206-Targeted Peptide for PET Imaging of Macrophages in Syngeneic Mouse Models of Cancer. Mol Pharm. 2023 05 01; 20(5):2415-2425.

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Ndemazie NB, Bulusu R, Zhu XY, Frimpong EK, Inkoom A, Okoro J, Ebesoh D, Rogers S, Han B, Agyare E. Evaluation of Anticancer Activity of Zhubech, a New 5-FU Analog Liposomal Formulation, against Pancreatic Cancer. Int J Mol Sci. 2023 Feb 21; 24(5).

View in: PubMed
Deng C, Wang Y, Navarro G, Sun Y, Cota-Ruiz K, Hernandez-Viezcas JA, Niu G, Li C, White JC, Gardea-Torresdey J. Copper oxide (CuO) nanoparticles affect yield, nutritional quality, and auxin associated gene expression in weedy and cultivated rice (Oryza sativa L.) grains. Sci Total Environ. 2022 Mar 01; 810:152260.

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Cao JY, Wang B, Tang TT, Wen Y, Li ZL, Feng ST, Wu M, Liu D, Yin D, Ma KL, Tang RN, Wu QL, Lan HY, Lv LL, Liu BC. Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury. Theranostics. 2021; 11(11):5248-5266.

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Li J, Canseco D, Wang Y, Vale G, Chaudhary J, Anwar A, Baniasadi H, Williams NS, Gopal P, Sutphin PD, McDonald JG, Putnam WC, Corbin IR. Assessing the safety of transarterial locoregional delivery of low-density lipoprotein docosahexaenoic acid nanoparticles to the rat liver. Eur J Pharm Biopharm. 2021 Jan; 158:273-283.

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Deng C, Wang Y, Cota-Ruiz K, Reyes A, Sun Y, Peralta-Videa J, Hernandez-Viezcas JA, Turley RS, Niu G, Li C, Gardea-Torresdey J. Bok choy (Brassica rapa) grown in copper oxide nanoparticles-amended soils exhibits toxicity in a phenotype-dependent manner: Translocation, biodistribution and nutritional disturbance. J Hazard Mater. 2020 11 05; 398:122978.

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Shivange G, Mondal T, Lyerly E, Gatesman J, Tushir-Singh J. Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody. J Vis Exp. 2020 05 16; (159).

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Ekpenyong O, Gao X, Ma J, Cooper C, Nguyen L, Olaleye OA, Liang D, Xie H. Pre-Clinical Pharmacokinetics, Tissue Distribution and Physicochemical Studies of CLBQ14, a Novel Methionine Aminopeptidase Inhibitor for the Treatment of Infectious Diseases. Drug Des Devel Ther. 2020; 14:1263-1277.

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